Berry antioxidants in health and disease / / edited by Dorothy Klimis-Zacas.

• TeilnehmendeR: Klimis-Zacas, Dorothy,
• Place / Publishing House: Basel, Switzerland : : MDPI - Multidisciplinary Digital Publishing Institute,, 2017.
• Year of Publication: 2017
• Language: English
• Physical Description: 1 online resource (viii, 156 pages) :; illustrations

During the last decade, a high volume of work has been published on the health-promoting effects of berries (e.g., blueberries, cranberries, blackberries, etc.) that are rich in antioxidant phytochemicals, polyphenols. Consuming a diet rich in polyphenols has been documented to attenuate the risk of chronic diseases, such as cardiovascular disease, certain cancers, diabetes mellitus, and neurodegenerative disorders. Recent evidence also reveals that the biological effects of polyphenols extend beyond their traditional antioxidant role. This Special Issue includes 10 peer-reviewed papers, including original research papers and reviews. They present the most recent advances in the role of berry antioxidants, not only in maintaining health but also in preventing and/or reversing disease both in cell culture, animal models and in humans. Additionally, the molecular mechanisms and signaling pathways modulated by berry antioxidants are presented. Chapters include the role of berry antioxidants in whole fruit and leaves on the metabolic syndrome, obesity, diabetes and glucose intolerance, cancer, inflammation, oxidative stress and neuroprotection as well as cardiovascular disease. As a guest editor, I would like to acknowledge the authors of all chapters for their valuable contributions and reviewers for their thoughtful and constructive suggestions and time. Special thanks to the publishing team of the Antioxidants Journal for their professionalism, attention to detail and timely completion of this volume.

Table of Contents

About the Guest Editor -- Preface to "Berry Antioxidants in Health and Disease" -- Berry Fruit Consumption and Metabolic Syndrome, Reprinted from: Antioxidants 2016, 5(4), 34; doi:10.3390/antiox5040034, http://www.mdpi.com/2076-3921/5/4/34 -- Recent Progress in Anti-Obesity and Anti-Diabetes Effect of Berries, Reprinted from: Antioxidants 2016, 5(2), 13; doi:10.3390/antiox5020013, http://www.mdpi.com/2076-3921/5/2/13 -- Blueberries' Impact on Insulin Resistance and Glucose Intolerance, Reprinted from: Antioxidants 2016, 5(4), 44; doi:10.3390/antiox5040044, http://www.mdpi.com/2076-3921/5/4/44 -- Blueberry Consumption Affects Serum Uric Acid Concentrations in Older Adults in a Sex-Specific Manner, Reprinted from: Antioxidants 2016, 5(4), 43; doi:10.3390/antiox5040043, http://www.mdpi.com/2076-3921/5/4/43 -- Protective Role of Dietary Berries in Cancer, Reprinted from: Antioxidants 2016, 5(4), 37; doi:10.3390/antiox5040037, http://www.mdpi.com/2076-3921/5/4/37 -- Cranberries and Cancer: An Update of Preclinical Studies Evaluating the Cancer Inhibitory Potential of Cranberry and Cranberry Derived Constituents, Reprinted from: Antioxidants 2016, 5(3), 27; doi:10.3390/antiox5030027, http://www.mdpi.com/2076-3921/5/3/27 -- Tart Cherry Extracts Reduce Inflammatory and Oxidative Stress Signaling in Microglial Cells, Reprinted from: Antioxidants 2016, 5(4), 33; doi:10.3390/antiox5040033, http://www.mdpi.com/2076-3921/5/4/33 -- Chemical Analysis of Extracts from Newfoundland Berries and Potential Neuroprotective Effects, Reprinted from: Antioxidants 2016, 5(4), 36; doi:10.3390/antiox5040036, http://www.mdpi.com/2076-3921/5/4/36 -- Berry Leaves: An Alternative Source of Bioactive Natural Products of Nutritional and Medicinal Value, Reprinted from: Antioxidants 2016, 5(2), 17; doi:10.3390/antiox5020017, http://www.mdpi.com/2076-3921/5/2/17 -- Anthocyanin Accumulation in Muscadine Berry Skins Is Influenced by the Expression of the MYB Transcription Factors, MybA1, and MYBCSI, Reprinted from: Antioxidants 2016, 5(4), 35; doi:10.3390/antiox5040035, http://www.mdpi.com/2076-3921/5/4/35.