Biophysical Theory of Radiation Action : : A Treatise on Relative Biological Effectiveness / / Wolfgang Schulz, Klaus Günther.

• VerfasserIn: Günther, Klaus,; Schulz, Wolfgang,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2022]; ©1983
• Year of Publication: 2022
• Edition: Reprint 2022
• Language: German
• Physical Description: 1 online resource (368 p.) :; with 80 Figures and 32 Tables
• Other title: Frontmatter --; Preface --; Contents --; Chapter 1 Review of theoretical conceptions --; 1.1. Introduction --; 1.2. Classical target theory --; 1.3. The LET concept --; 1.4. Microdosimetry --; 1.5. Gross sensitive volume with structure --; 1.6. Some descriptive approaches to survival curves and RBE --; Chapter 2 An approximate approach based on microdosimetry --; 2.1. Introduction --; 2.2. Formalism of the microdosimetric version of theory --; 2.3. Theoretical consequences for the relative biological effectiveness --; 2.4. Analysis of experimental data --; 2.5. Primary lesions and the relevant RBE --; 2.6. Appendix --; Chapter 3 The mathematical formalism of the DNA-lesion theory of radiation action --; 3.1. Introduction --; 3.2. Prerequisites and basic principles of approximation --; 3.3. Description of radiation fields --; 3.4. Description of absorption events --; 3.5. The model of DNA-lesion production --; 3.6. The theory of cellular radiation effects --; 3.7. Formal properties and consistency of the theory --; 3.8. Appendix: estimation of errors --; Chapter 4 The underlying physical relationships --; 4.1. Introduction --; 4.2. Linear energy transfer --; 4.3. Energy spectrum of 8-rays --; 4.4. Primary ionizations and ionization cluster frequencies --; 4.5. Electron range --; 4.6. Secondary electron spectrum of photon radiation --; 4.7. Secondary charged particle spectra of fast neutrons --; Chapter 5 Implications concerning microdosimetry --; 5.1. Introduction --; 5.2. The mathematical formalism --; 5.3. Comparison with experimental data --; Chapter 6 Evaluation of the model of DNA-lesion production --; 6.1. Introduction --; 6.2. Methodic particulars --; 6.3. General results --; 6.4. DNA-strand breaks --; Chapter 7 Mammalian cell killing --; 7.1. Introduction --; 7.2. Survival curve analysis for monoenergetic ion radiations --; 7.3. Ion radiations --; 7.4. Fast neutron radiations --; Chapter 8 Re-formulation of the theory --; 8.1. Introduction --; 8.2. Virtual mierodosimetry --; 8.3. The ultimate general formalism of the theory of cellular radiation effects --; 8.4. Evaluation of RBE in LETapproximation for monoenergetic ions --; Chapter 9 Concise instructions for practical calculations --; 9.1. Introduction --; 9.2. Calculation of dose-effect relations --; 9.3. Expressing a dose-effect relation by a sum of exponential functions --; Appendix --; References --; Subject index
• Format: Mode of access: Internet via World Wide Web.
• ISBN: 9783112618943
• DOI: 10.1515/9783112618943
• Access: restricted access
• Hierarchical level: Monograph
• Statement of Responsibility: Wolfgang Schulz, Klaus Günther.