Basic and clinical aspects of immunity to insulin : : Proceedings, International Workshop, September 28–October 1, 1980, Konstanz / / ed. by Klaus Keck, P. Erb.
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Table of Contents:
- Frontmatter
- PREFACE
- LIST OF PARTICIPANTS
- CONTENTS
- SECTION I. BASIC ASPECTS OF IMMUNITY TO INSULIN
- Introduction: Insulin as a tool for the study of immunological problems
- Genetic control of the immune response to insulin
- Analysis of the in vitro induction of insulin-specific helper T cells
- Immunogenic determinants of insulin: Synthesis and immunogenicity of the A-chain loop peptides of beef insulin
- Analysis of H-2 gene regulation of the response of T lymphocytes to insulin using synthetic antigenic determinants and anti-idiotypes
- Ir gene control of the insulin-specific immune response in mice
- Influence of insulin modification upon the immune response to insulin
- Function and complementation of Ir genes controlling the responsiveness of mice to insulin
- The XID gene controls Ia.W39 associated immune response gene function for insulin induced T cell activation
- Induction of immunity and suppression by pig insulin in mice
- Genetic control of anti-insulin responses is associated with activation of different T-cell sets
- Suppression of insulin responses in vitro
- Immune response phenotype of insulin-presenting cells modified by insertion of H-2 gene products into cell membranes
- Differences in insulin antibodies induced with varying antigenic forms
- Mouse hybridoma antibody recognition of the insulin molecule
- SECTION II. CLINICAL ASPECTS OF IMMUNITY TO INSULIN
- Clinical aspects of immunity to insulin
- Antibody production during insulin therapy - patterns of response and clinical sequels
- Studies of the immunogenicity of chromatographically purified insulins in Type-I and Type-II diabetics
- Genetic control of the IgE response to insulin
- HLA-DR association of humoral immunoresponsiveness to insulin in insulin-dependent (Type I) diabetes mellitus
- Insulin antibody formation following conventional or monocomponent insulin treatment is influenced by genes of the HLA-DR locus
- A study of HLA alloantigen frequencies in insulin allergic and non-allergic diabetics
- Morphologic changes in pancreas islets after active or passive immunization against insulin: a review
- The role of autoimmune processes in the development of insulin-dependent diabetes mellitus in mice treated with streptozotocin
- Effect of insulin-binding antibodies of free insulin in plasma and tissue after subcutaneous injection. A model study
- Immunogenicity of insulin in relation to its physicochemical properties
- Potentation of insulin immunogenicity by different types of adjuvant
- Use of modified insulins for the separation of insulin antibodies by affinity chromatography
- The immunogenicity of insulin from our point of view
- SECTION III. CHEMISTRY TO INSULIN
- Preparation of insulins with modified N-terminals by semisynthesis and chemical modification of the native hormone
- Synthesis of insulin analogues
- Modification of the C-terminal region of insulin
- SUBJECT INDEX
- AUTHOR INDEX
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