Chemistry of Nucleic Acids / / Harri Lönnberg.
Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their...
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| Place / Publishing House: | Berlin ;, Boston : : De Gruyter, , [2020] ©2020 |
| Year of Publication: | 2020 |
| Language: | English |
| Series: | De Gruyter Textbook
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| Physical Description: | 1 online resource (XI, 353 p.) |
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Lönnberg, Harri, author. aut http://id.loc.gov/vocabulary/relators/aut Chemistry of Nucleic Acids / Harri Lönnberg. Berlin ; Boston : De Gruyter, [2020] ©2020 1 online resource (XI, 353 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda De Gruyter Textbook Frontmatter -- Preface -- Contents -- 1 Nucleosides: structure, nomenclature and solution equilibria -- 2 Nucleosides: synthesis, reactions and use in chemotherapy -- 3 Nucleotides -- 4 Oligonucleotides: synthesis -- 5 Oligonucleotides: reactions of phosphodiester linkages -- 6 Oligonucleotide conjugates -- 7 Nucleic acids -- 8 Catalytic nucleic acids -- 9 Nucleic acids as drugs and drug targets 1: antisense, splice-switching, triplex-forming and immune-stimulatory oligonucleotides -- 10 Nucleic acids as drugs and drug targets 2: RNA interference, 2′,5′-oligoadenylates and riboswitches -- 11 Nucleic acids as drugs and drug targets 3: target recognition and delivery -- Abbreviations -- Index restricted access http://purl.org/coar/access_right/c_16ec online access with authorization star Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their structural analogues used as therapeutic drugs, such as antivirals and anticancer agents, and prodrug strategies of nucleotides. Issued also in print. Mode of access: Internet via World Wide Web. In English. Description based on online resource; title from PDF title page (publisher's Web site, viewed 27. Jan 2023) Medizinische Biochemie. Nucleinsäuren. Nucleinsäurestoffwechsel. Pro-Pharmakon. SCIENCE / Life Sciences / Biochemistry. bisacsh Biochemistry. Medical Biochemistry. Nucleic Acid Metabolism. Nucleic Acids. Title is part of eBook package: De Gruyter DG Ebook Package English 2020 9783110696288 Title is part of eBook package: De Gruyter DG Plus DeG Package 2020 Part 1 9783110696271 Title is part of eBook package: De Gruyter De Gruyter English eBooks 2020 - UC 9783110659061 Title is part of eBook package: De Gruyter EBOOK PACKAGE COMPLETE 2020 English 9783110704716 Title is part of eBook package: De Gruyter EBOOK PACKAGE COMPLETE 2020 9783110704518 ZDB-23-DGG Title is part of eBook package: De Gruyter EBOOK PACKAGE Physics, Chemistry, Mat.Sc, Geosc 2020 English 9783110704754 Title is part of eBook package: De Gruyter EBOOK PACKAGE Physics, Chemistry, Mat.Sc, Geosc 2020 9783110704556 ZDB-23-DPC EPUB 9783110613988 print 9783110609271 https://doi.org/10.1515/9783110609295 https://www.degruyter.com/isbn/9783110609295 Cover https://www.degruyter.com/document/cover/isbn/9783110609295/original |
| language |
English |
| format |
eBook |
| author |
Lönnberg, Harri, Lönnberg, Harri, |
| spellingShingle |
Lönnberg, Harri, Lönnberg, Harri, Chemistry of Nucleic Acids / De Gruyter Textbook Frontmatter -- Preface -- Contents -- 1 Nucleosides: structure, nomenclature and solution equilibria -- 2 Nucleosides: synthesis, reactions and use in chemotherapy -- 3 Nucleotides -- 4 Oligonucleotides: synthesis -- 5 Oligonucleotides: reactions of phosphodiester linkages -- 6 Oligonucleotide conjugates -- 7 Nucleic acids -- 8 Catalytic nucleic acids -- 9 Nucleic acids as drugs and drug targets 1: antisense, splice-switching, triplex-forming and immune-stimulatory oligonucleotides -- 10 Nucleic acids as drugs and drug targets 2: RNA interference, 2′,5′-oligoadenylates and riboswitches -- 11 Nucleic acids as drugs and drug targets 3: target recognition and delivery -- Abbreviations -- Index |
| author_facet |
Lönnberg, Harri, Lönnberg, Harri, |
| author_variant |
h l hl h l hl |
| author_role |
VerfasserIn VerfasserIn |
| author_sort |
Lönnberg, Harri, |
| title |
Chemistry of Nucleic Acids / |
| title_full |
Chemistry of Nucleic Acids / Harri Lönnberg. |
| title_fullStr |
Chemistry of Nucleic Acids / Harri Lönnberg. |
| title_full_unstemmed |
Chemistry of Nucleic Acids / Harri Lönnberg. |
| title_auth |
Chemistry of Nucleic Acids / |
| title_alt |
Frontmatter -- Preface -- Contents -- 1 Nucleosides: structure, nomenclature and solution equilibria -- 2 Nucleosides: synthesis, reactions and use in chemotherapy -- 3 Nucleotides -- 4 Oligonucleotides: synthesis -- 5 Oligonucleotides: reactions of phosphodiester linkages -- 6 Oligonucleotide conjugates -- 7 Nucleic acids -- 8 Catalytic nucleic acids -- 9 Nucleic acids as drugs and drug targets 1: antisense, splice-switching, triplex-forming and immune-stimulatory oligonucleotides -- 10 Nucleic acids as drugs and drug targets 2: RNA interference, 2′,5′-oligoadenylates and riboswitches -- 11 Nucleic acids as drugs and drug targets 3: target recognition and delivery -- Abbreviations -- Index |
| title_new |
Chemistry of Nucleic Acids / |
| title_sort |
chemistry of nucleic acids / |
| series |
De Gruyter Textbook |
| series2 |
De Gruyter Textbook |
| publisher |
De Gruyter, |
| publishDate |
2020 |
| physical |
1 online resource (XI, 353 p.) Issued also in print. |
| contents |
Frontmatter -- Preface -- Contents -- 1 Nucleosides: structure, nomenclature and solution equilibria -- 2 Nucleosides: synthesis, reactions and use in chemotherapy -- 3 Nucleotides -- 4 Oligonucleotides: synthesis -- 5 Oligonucleotides: reactions of phosphodiester linkages -- 6 Oligonucleotide conjugates -- 7 Nucleic acids -- 8 Catalytic nucleic acids -- 9 Nucleic acids as drugs and drug targets 1: antisense, splice-switching, triplex-forming and immune-stimulatory oligonucleotides -- 10 Nucleic acids as drugs and drug targets 2: RNA interference, 2′,5′-oligoadenylates and riboswitches -- 11 Nucleic acids as drugs and drug targets 3: target recognition and delivery -- Abbreviations -- Index |
| isbn |
9783110609295 9783110696288 9783110696271 9783110659061 9783110704716 9783110704518 9783110704754 9783110704556 9783110613988 9783110609271 |
| url |
https://doi.org/10.1515/9783110609295 https://www.degruyter.com/isbn/9783110609295 https://www.degruyter.com/document/cover/isbn/9783110609295/original |
| illustrated |
Not Illustrated |
| doi_str_mv |
10.1515/9783110609295 |
| oclc_num |
1191864281 |
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AT lonnbergharri chemistryofnucleicacids |
| status_str |
n |
| ids_txt_mv |
(DE-B1597)497769 (OCoLC)1191864281 |
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cr |
| hierarchy_parent_title |
Title is part of eBook package: De Gruyter DG Ebook Package English 2020 Title is part of eBook package: De Gruyter DG Plus DeG Package 2020 Part 1 Title is part of eBook package: De Gruyter De Gruyter English eBooks 2020 - UC Title is part of eBook package: De Gruyter EBOOK PACKAGE COMPLETE 2020 English Title is part of eBook package: De Gruyter EBOOK PACKAGE COMPLETE 2020 Title is part of eBook package: De Gruyter EBOOK PACKAGE Physics, Chemistry, Mat.Sc, Geosc 2020 English Title is part of eBook package: De Gruyter EBOOK PACKAGE Physics, Chemistry, Mat.Sc, Geosc 2020 |
| is_hierarchy_title |
Chemistry of Nucleic Acids / |
| container_title |
Title is part of eBook package: De Gruyter DG Ebook Package English 2020 |
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1770177715674021888 |
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