Chemistry of Nucleic Acids /

Chemistry of Nucleic Acids / / Harri Lönnberg.

Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their...

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Bibliographic Details
Superior document:Title is part of eBook package: De Gruyter DG Ebook Package English 2020
VerfasserIn:
Lönnberg, Harri,
Place / Publishing House:Berlin ;, Boston : : De Gruyter, , [2020]
©2020
Year of Publication:2020
Language:English
Series:De Gruyter Textbook
Online Access:
Physical Description:1 online resource (XI, 353 p.)
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245 1 0 |a Chemistry of Nucleic Acids /  |c Harri Lönnberg. 
264 1 |a Berlin ;  |a Boston :   |b De Gruyter,   |c [2020] 
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300 |a 1 online resource (XI, 353 p.) 
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505 0 0 |t Frontmatter --   |t Preface --   |t Contents --   |t 1 Nucleosides: structure, nomenclature and solution equilibria --   |t 2 Nucleosides: synthesis, reactions and use in chemotherapy --   |t 3 Nucleotides --   |t 4 Oligonucleotides: synthesis --   |t 5 Oligonucleotides: reactions of phosphodiester linkages --   |t 6 Oligonucleotide conjugates --   |t 7 Nucleic acids --   |t 8 Catalytic nucleic acids --   |t 9 Nucleic acids as drugs and drug targets 1: antisense, splice-switching, triplex-forming and immune-stimulatory oligonucleotides --   |t 10 Nucleic acids as drugs and drug targets 2: RNA interference, 2′,5′-oligoadenylates and riboswitches --   |t 11 Nucleic acids as drugs and drug targets 3: target recognition and delivery --   |t Abbreviations --   |t Index 
506 0 |a restricted access  |u http://purl.org/coar/access_right/c_16ec  |f online access with authorization  |2 star 
520 |a Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their structural analogues used as therapeutic drugs, such as antivirals and anticancer agents, and prodrug strategies of nucleotides. 
530 |a Issued also in print. 
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546 |a In English. 
588 0 |a Description based on online resource; title from PDF title page (publisher's Web site, viewed 27. Jan 2023) 
650 4 |a Medizinische Biochemie. 
650 4 |a Nucleinsäuren. 
650 4 |a Nucleinsäurestoffwechsel. 
650 4 |a Pro-Pharmakon. 
650 7 |a SCIENCE / Life Sciences / Biochemistry.  |2 bisacsh 
653 |a Biochemistry. 
653 |a Medical Biochemistry. 
653 |a Nucleic Acid Metabolism. 
653 |a Nucleic Acids. 
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