Hepatobiliary Transport in Health and Disease /

Hepatobiliary Transport in Health and Disease / / ed. by Dieter Häussinger, Ralf Kubitz, Verena Keitel.

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One major function of the liver is the uptake of endo- and xenobiotics from the bloodstream and their excretion into bile. The transport systems involved in hepatobiliary transport have been recently cloned and characterized at the molecular level and it is becoming clear that mutations and polymorp...

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Superior document:Title is part of eBook package: De Gruyter DGBA Backlist Complete English Language 2000-2014 PART1
MitwirkendeR:
Baghdasaryan, Anna,
Beuers, Ulrich,
Bode, Johannes,
Claudel, Thierry,
Ellinger, Philipp,
Fabris, Luca,
Gadaleta, Raffaella,
Graf, Dirk,
Herebian, Diran,
Hohenester, Simon,
Hov, Johannes Roksund,
Häussinger, Dieter,
Karlsen, Tom Hemming,
Keitel, Verena,
Keppler, Dietrich,
Kluth, Marianne,
Kubitz, Ralf,
Lammert, Frank,
Mayatepek, Ertan,
Meier, Peter J.,
Moschetta, Antonio,
Müllenbach, Roman,
Pauli-Magnus, Christiane,
Przybylla, Susanne,
Raizner, Aileen,
Reinehr, Roland,
Schmitt, Lutz,
Schrumpf, Erik,
Smits, Sander H. J.,
Stieger, Bruno,
Strazzabosco, Mario,
Trauner, Michael,
Wittenburg, Henning,
HerausgeberIn:
Häussinger, Dieter,
Keitel, Verena,
Kubitz, Ralf,
Place / Publishing House:Berlin ;, Boston : : De Gruyter, , [2012]
©2012
Year of Publication:2012
Language:English
Online Access:
Physical Description:1 online resource (292 p.)
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Table of Contents:
  • Frontmatter
  • Preface
  • List of Contributors
  • Contents
  • Abbreviations
  • 1 Physiology of bile formation: Hepatocellular bile salt transporters
  • 2 Structure and function of hepatic ABC transporters
  • 3 Short- and long-term regulation of hepatobiliary transport
  • 4 Nuclear bile acid receptor FXR and hepatobiliary transport systems
  • 5 Bile acid signaling in the liver and the biliary tree
  • 6 Modulation of innate immunity and inflammation by bile acids and their receptors
  • 7 Bile acids as extrahepatic and interorgan signaling molecules
  • 8 Disorders of bile duct development
  • 9 Mutations of the bile salt export pump (BSEP) and multidrug-resistance protein 3 (MDR3)
  • 10 MRP2 (ABCC2) and disorders of bilirubin handling in liver
  • 11 Hepatobiliary transport during pregnancy: Crosstalk between transporters and hormones
  • 12 Hepatobiliary transport and gallstone formation
  • 13 Molecular basis of primary biliary cirrhosis
  • 14 The molecular basis of primary sclerosing cholangitis
  • 15 Drug-induced cholestatic liver injury
  • 16 Bile acids and receptors: Therapeutic relevance
  • 17 Analysis of bile acids by tandem mass spectrometry
  • Index

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