Liver Regeneration / / ed. by Dieter Häussinger.

• Superior document: Title is part of eBook package: De Gruyter DGBA Backlist Complete English Language 2000-2014 PART1
• MitwirkendeR: Bode, Johannes G.,; Buschmann, Tobias,; Choi, Steve S.,; DeFrances, Marie C.,; Diehl, Anna Mae,; Drasdo, Dirk,; Eglinger, Jan,; Esch, Jan Schulte am,; Fürst, Günter,; Gasbarrini, Antonio,; Gebhardt, Rolf,; Hengstler, Jan G.,; Hoehme, Stefan,; Hovhannisyan, Amalya,; Häussinger, Dieter,; Knoefel, Wolfram Trudo,; Kordes, Claus,; Lammert, Eckhard,; Michalopoulos, George K.,; Petersen, Bryon E.,; Pfeffer, Klaus,; Piscaglia, Anna C.,; Reinehr, Roland,; Sawitza, Iris,; Schmelzle, Moritz,; Sorg, Ursula R.,
• HerausgeberIn: Häussinger, Dieter,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2011]; ©2011
• Year of Publication: 2011
• Language: English
• Series: De Gruyter Textbook
• Physical Description: 1 online resource (214 p.)
• Other title: Frontmatter --; Preface --; Contents --; Author Index --; Abbreviations --; 1 Liver Regeneration and Partial Hepatectomy: Process and Prototype --; 2 Oval Cells, Bone Marrow, and Liver Regeneration --; 3 Inflammation and Liver Regeneration --; 4 Lymphotoxin β Receptor and Tumor Necrosis Factor Receptor p55 in Liver Regeneration --; 5 The Hepatic Stem Cell Niches --; 6 Stellate Cells in the Regenerating Liver --; 7 Epigenetics during Liver Regeneration --; 8 Hedgehog Signaling and Liver Regeneration --; 9 EGFR, CD95, and the Switch between Proliferation and Apoptosis in Hepatic Stellate Cells --; 10 Angiogenesis and Liver Regeneration --; 11 A Quantitative Mathematical Modeling Approach to Liver Regeneration --; 12 Animal Models for Studies on Liver Regeneration --; 13 Therapeutic Potential of Bone Marrow Stem Cells in Liver Surgery --; Index
• Format: Mode of access: Internet via World Wide Web.
• ISBN: 9783110250794; 9783110238570; 9783110238495; 9783110637915; 9783110261189; 9783110261233; 9783110261202
• DOI: 10.1515/9783110250794
• Access: restricted access
• Hierarchical level: Monograph
• Statement of Responsibility: ed. by Dieter Häussinger.

understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.