Applications of toxicogenomics in safety evaluation and risk assessment / edited by Darrell R. Boverhof, B. Bhaskar Gollapudi.
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Year of Publication: | 2011 |
Language: | English |
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Physical Description: | xiii, 377 p., [8] p. of plates :; ill. (some col.) |
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020 | |z 9781118001042 (oBook) | ||
020 | |a 9781118001035 (electronic bk.) | ||
020 | |a 9781118008980 (electronic bk.) | ||
020 | |a 9781118001035 (electronic bk.) | ||
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082 | 0 | 4 | |a 616/.042 |2 22 |
245 | 0 | 0 | |a Applications of toxicogenomics in safety evaluation and risk assessment |h [electronic resource] / |c edited by Darrell R. Boverhof, B. Bhaskar Gollapudi. |
260 | |a Hoboken, N.J. : |b John Wiley & Sons, |c c2011. | ||
300 | |a xiii, 377 p., [8] p. of plates : |b ill. (some col.) | ||
504 | |a Includes bibliographical references and index. | ||
505 | 0 | |a Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan - -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach. | |
533 | |a Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. | ||
650 | 0 | |a Genetic toxicology. | |
650 | 0 | |a Toxicity testing. | |
650 | 0 | |a Health risk assessment. | |
655 | 4 | |a Electronic books. | |
700 | 1 | |a Boverhof, Darrell R. | |
700 | 1 | |a Gollapudi, B. Bhaskar. | |
710 | 2 | |a ProQuest (Firm) | |
856 | 4 | 0 | |u https://ebookcentral.proquest.com/lib/oeawat/detail.action?docID=693202 |z Click to View |