Xenopus : : from basic biology to disease models in the genomic era /

Xenopus : : from basic biology to disease models in the genomic era / / edited by Abraham Fainsod, Sally A. Moody.

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"Xenopus is unique among the model animals used in the biology. Several books of protocols used Xenopus. Missing is a book taking an historical perspective documenting cell and developmental discoveries and illustrating how Xenopus contributes to the understanding of genes. These topics will be...

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Bibliographic Details
TeilnehmendeR:
Fainsod, Abraham,
Moody, Sally A.,
Place / Publishing House:Boca Raton : : Taylor & Francis,, 2022.
©2022
Year of Publication:2022
Language:English
Physical Description:1 online resource (360 pages)
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Table of Contents:
  • Section I.
  • 1. A quick history of Xenopus.
  • 2. The study of cell division controla and DNA replication in Xenopus egg extracts.
  • 3. Maternal gene control of embryogenesis: germ cell determination and germ layer formation.
  • 4. Signaling components in dorsal-ventral patterning and the Organizer.
  • 5. Signaling pathways in anterior-posterior patterning.
  • 6. Wnt signaling in tissue differentiation and morphogenesis.
  • 7. Multiple functions of Notch signaling during early embryogenesis.
  • 8. The development and evolution of the vertebrate neural crest: Insights from Xenopus.
  • 9. The use of Xenopus oocytes to study the biophysics and pharmacological properties of receptors and channels.
  • Section II.
  • 10. The continuing evolution of the Xenopus genome.
  • 11. Dynamics of chromatin remodeling during Xenopus development.
  • 12. Gene regulatory networks controlling Xenopus embryogenesis.
  • 13. The development of high-resolution proteomic analyses in Xenopus.
  • 14. Advances in genome editing tools.
  • Section III.
  • 15. Formation of the left-right axis: insights from the Xenopus model.
  • 16. Discovering the function of congenital heart disease genes.
  • 17. Craniofacial development and disorders - contributions of Xenopus.
  • 18. Modeling digestive and respiratory system development and disease in Xenopus.
  • 19. Functional neurobiology and insights into human disease.
  • 20. Leaping towards the understanding of spinal cord regeneration.
  • 21. Studying tumor formation and regulation in Xenopus.
  • 22. Xenopus: a model to study natural genetic variation and its disease implications.
  • 23. Using Xenopus to understand pluripotency and reprogram cells for therapeutic use. Maternal gene control of embryogenesis.
  • Chapter 8: Sex determination in Xenopus.
  • Section II: Gene Discovery and Disease.
  • Chapter 9: Xenopus and the discovery of developmental genes.
  • Chapter 10: Systems Biology of Xenopus Embryogenesis.
  • Chapter 11: Gene regulatory networks in craniofacial development.
  • Chapter 12: Using Xenopus to discover regulation of GI development and disease.
  • Chapter 13: Using Xenopus to discover the function of congenital heart disease genes.
  • Chapter 14: Using Xenopus to discover the function of congenital kidney disease genes.
  • Chapter 15: Using Xenopus to study genes involved in cancers.
  • Section III: Evolution. Chapter 16: Evolution of amphibians. Chapter 17: Evolution of Xenopus communication. Chapter 18: Evolution of the immune system .
  • Chapter 19: Evolution of the left-right axis.
  • Chapter 20: Evolution of the Xenopus genome.

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