O-GlcNAcylation and cancer /

O-GlcNAcylation and cancer / / Ikram El Yazidi-Belkoura, Tony Lefebvre, (editors).

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his book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription...

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Bibliographic Details
TeilnehmendeR:
Lefebvre, Tony ,
El Yazidi-Belkoura, Ikram,
Place / Publishing House:Basel : : MDPI - Multidisciplinary Digital Publishing Institute,, [2022]
©2022
Year of Publication:2022
Language:English
Physical Description:1 online resource (112 pages)
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Table of Contents:
  • 1. Introduction
  • 2. O-GlcNAcylation
  • 2.2. Functions of O-GlcNAcylation
  • 3. O-GlcNAcylation and Cancer
  • 3.1. O-GlcNAcylation and Metastasis
  • 3.2. O-GlcNAcylation and Receptor Tyrosine Kinase
  • 3.3. O-GlcNAcylation and Resistance to Chemotherapy
  • 3.4. O-GlcNAcylation as Prognostic Marker
  • 4. O-GlcNAcylation and Immune Responses in Cancer
  • 4.1. Overview of Immune System and O-GlcNAcylation
  • 4.2. T Cell Activation and Differentiation Regulated by O-GlcNAcylation
  • 4.3. Macrophage Differentiation and Activation by O-GlcNAcylation
  • 4.4. O-GlcNAcylation and Tumor Microenvironment
  • 5. Cancer Therapeutics Targeting O-GlcNAcylation
  • 6. Conclusions and Future Perspectives
  • Author Contributions
  • Funding
  • Conflicts of Interest
  • Footnotes
  • References.

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