Molecular imaging in Parkinson's Disease / / Cristina Polito.
The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Florence underwent clinical assessment, neuropsychological...
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| Superior document: | Premio Firenze University Press tesi di dottorato (Series), ; 18 |
|---|---|
| VerfasserIn: | |
| Place / Publishing House: | Firenze : : Firenze University Press,, 2011 |
| Year of Publication: | 2011 |
| Language: | Italian |
| Series: | Premio Firenze University Press tesi di dottorato (Series) ;
18. |
| Physical Description: | 1 online resource (68 pages) :; illustrations; digital, PDF file(s). |
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| 100 | 1 | |a Polito, Cristina, |e author. | |
| 245 | 1 | 0 | |a Molecular imaging in Parkinson's Disease / |c Cristina Polito. |
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| 300 | |a 1 online resource (68 pages) : |b illustrations; digital, PDF file(s). | ||
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| 490 | 1 | |a Premio Firenze University Press tesi di dottorato (Series), ; |v 18 | |
| 504 | |a Includes bibliographical references. | ||
| 506 | 0 | |a Open Access |f Unrestricted online access |2 star | |
| 520 | |a The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Florence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET. First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus. | ||
| 530 | |a Also available in print form. | ||
| 655 | 4 | |b Electronic books. | |
| 650 | 0 | |a Parkinson's disease. | |
| 776 | 0 | 8 | |i Print version: |z 9788866550372 |
| 830 | 0 | |a Premio Firenze University Press tesi di dottorato (Series) ; |v 18. | |
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