Study of intracellular signaling pathways in Chronic Myeloproliferative Neoplasms / / Serena Martinelli.
A gain-of-function mutation in Janus kinase 2 (JAK2V617F) is at the basis of the majority of chronic myeloproliferative neoplasms (MPN). Enhanced activation of other downstream pathways including the PI3K/mTOR pathway has been documented as well. In this study we evaluated the effects of JAK1/2 inhi...
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Place / Publishing House: | Firenze : : Firenze University Press,, 2017. |
Year of Publication: | 2017 |
Language: | English |
Physical Description: | 1 online resource (75 pages) |
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