Study of intracellular signaling pathways in Chronic Myeloproliferative Neoplasms / / Serena Martinelli.

A gain-of-function mutation in Janus kinase 2 (JAK2V617F) is at the basis of the majority of chronic myeloproliferative neoplasms (MPN). Enhanced activation of other downstream pathways including the PI3K/mTOR pathway has been documented as well. In this study we evaluated the effects of JAK1/2 inhi...

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Place / Publishing House:Firenze : : Firenze University Press,, 2017.
Year of Publication:2017
Language:English
Physical Description:1 online resource (75 pages)
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