Molecular Mechanism of Alzheimer's Disease

Molecular Mechanism of Alzheimer's Disease

Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, th...

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Macreadie, Ian
Year of Publication:2019
Language:English
Physical Description:1 electronic resource (228 p.)
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id 993548257504498
ctrlnum (CKB)4100000010106213
(oapen)https://directory.doabooks.org/handle/20.500.12854/53845
(EXLCZ)994100000010106213
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spelling Macreadie, Ian auth
Molecular Mechanism of Alzheimer's Disease
MDPI - Multidisciplinary Digital Publishing Institute 2019
1 electronic resource (228 p.)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer’s disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue.
English
HOTAIR
neurosciences
sleep disturbance
positron emission tomography (PET)
vitamin B complex
neurodegeneration
Tau
miR-15/107
default-mode network
complement receptor 1
neuronal differentiation
epigenetics
brain glucose metabolism
oligomerization
genetic risk
A?O receptors
prion
ryanodine receptor
type 3 diabetes
complement
cognitive behavioral therapy for insomnia
cognitive function
epigenome-wide association study
Alzheimer’s disease
calcium signaling
?-secretase
tau
Prolyl isomerases
NEAT1
complement C3b/C4b receptor
proteostasis
amyloid beta
yeast
slow-wave sleep
amyloid ?
nutrition
4
protein aggregation
apolipoprotein E
dementia
MALAT1
inositol 1
lncRNAs
molecular biology
methylenetetrahydrofolate reductase MTHFR gene
5-trisphosphate receptor
CR1 density
miR-34c
aggregation
heat shock protein
dendritic spine
S-adenosylmethionine
beta amyloid
ion channel
inflammation
sleep fragmentation
cystathionine-?-lyase CTH gene
DNA methylation
heat shock response
microglia
drug target discovery
amyloid-? oligomer
therapy
CR1 length polymorphism
methylome
APOE gene
ubiquitin
magnetic resonance imaging (MRI)
neuronal degeneration
type 2 diabetes
Pin1
mild cognitive impairment
dairy products
endoplasmic reticulum
oxidative stress
Hispanics
CDK5R1
3-03921-407-1
language English
format eBook
author Macreadie, Ian
spellingShingle Macreadie, Ian
Molecular Mechanism of Alzheimer's Disease
author_facet Macreadie, Ian
author_variant i m im
author_sort Macreadie, Ian
title Molecular Mechanism of Alzheimer's Disease
title_full Molecular Mechanism of Alzheimer's Disease
title_fullStr Molecular Mechanism of Alzheimer's Disease
title_full_unstemmed Molecular Mechanism of Alzheimer's Disease
title_auth Molecular Mechanism of Alzheimer's Disease
title_new Molecular Mechanism of Alzheimer's Disease
title_sort molecular mechanism of alzheimer's disease
publisher MDPI - Multidisciplinary Digital Publishing Institute
publishDate 2019
physical 1 electronic resource (228 p.)
isbn 3-03921-408-X
3-03921-407-1
illustrated Not Illustrated
work_keys_str_mv AT macreadieian molecularmechanismofalzheimersdisease
status_str n
ids_txt_mv (CKB)4100000010106213
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carrierType_str_mv cr
is_hierarchy_title Molecular Mechanism of Alzheimer's Disease
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