Molecular Mechanism of Alzheimer's Disease

Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, th...

Full description

Saved in:
Bibliographic Details
:
Year of Publication:2019
Language:English
Physical Description:1 electronic resource (228 p.)
Tags: Add Tag
No Tags, Be the first to tag this record!
LEADER 03880nam-a2201189z--4500
001 993548257504498
005 20231214133409.0
006 m o d
007 cr|mn|---annan
008 202102s2019 xx |||||o ||| 0|eng d
020 |a 3-03921-408-X 
035 |a (CKB)4100000010106213 
035 |a (oapen)https://directory.doabooks.org/handle/20.500.12854/53845 
035 |a (EXLCZ)994100000010106213 
041 0 |a eng 
100 1 |a Macreadie, Ian  |4 auth 
245 1 0 |a Molecular Mechanism of Alzheimer's Disease 
260 |b MDPI - Multidisciplinary Digital Publishing Institute  |c 2019 
300 |a 1 electronic resource (228 p.) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
520 |a Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer’s disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue. 
546 |a English 
653 |a HOTAIR 
653 |a neurosciences 
653 |a sleep disturbance 
653 |a positron emission tomography (PET) 
653 |a vitamin B complex 
653 |a neurodegeneration 
653 |a Tau 
653 |a miR-15/107 
653 |a default-mode network 
653 |a complement receptor 1 
653 |a neuronal differentiation 
653 |a epigenetics 
653 |a brain glucose metabolism 
653 |a oligomerization 
653 |a genetic risk 
653 |a A?O receptors 
653 |a prion 
653 |a ryanodine receptor 
653 |a type 3 diabetes 
653 |a complement 
653 |a cognitive behavioral therapy for insomnia 
653 |a cognitive function 
653 |a epigenome-wide association study 
653 |a Alzheimer’s disease 
653 |a calcium signaling 
653 |a ?-secretase 
653 |a tau 
653 |a Prolyl isomerases 
653 |a NEAT1 
653 |a complement C3b/C4b receptor 
653 |a proteostasis 
653 |a amyloid beta 
653 |a yeast 
653 |a slow-wave sleep 
653 |a amyloid ? 
653 |a nutrition 
653 |a 4 
653 |a protein aggregation 
653 |a apolipoprotein E 
653 |a dementia 
653 |a MALAT1 
653 |a inositol 1 
653 |a lncRNAs 
653 |a molecular biology 
653 |a methylenetetrahydrofolate reductase MTHFR gene 
653 |a 5-trisphosphate receptor 
653 |a CR1 density 
653 |a miR-34c 
653 |a aggregation 
653 |a heat shock protein 
653 |a dendritic spine 
653 |a S-adenosylmethionine 
653 |a beta amyloid 
653 |a ion channel 
653 |a inflammation 
653 |a sleep fragmentation 
653 |a cystathionine-?-lyase CTH gene 
653 |a DNA methylation 
653 |a heat shock response 
653 |a microglia 
653 |a drug target discovery 
653 |a amyloid-? oligomer 
653 |a therapy 
653 |a CR1 length polymorphism 
653 |a methylome 
653 |a APOE gene 
653 |a ubiquitin 
653 |a magnetic resonance imaging (MRI) 
653 |a neuronal degeneration 
653 |a type 2 diabetes 
653 |a Pin1 
653 |a mild cognitive impairment 
653 |a dairy products 
653 |a endoplasmic reticulum 
653 |a oxidative stress 
653 |a Hispanics 
653 |a CDK5R1 
776 |z 3-03921-407-1 
906 |a BOOK 
ADM |b 2023-12-15 05:52:55 Europe/Vienna  |f system  |c marc21  |a 2020-02-01 22:26:53 Europe/Vienna  |g false 
AVE |i DOAB Directory of Open Access Books  |P DOAB Directory of Open Access Books  |x https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338799830004498&Force_direct=true  |Z 5338799830004498  |b Available  |8 5338799830004498