Animal model studies on viral infections / Topic editors: Akio Adachi and Tomoyuki Miura.
Understanding viral replication and pathogenicity properties in infected individuals is a major mission of animal virology. Animal models are essential to analyze the in vivo viral characteristics and to develop countermeasures against viruses. To fight against a wide variety of viruses, basic studi...
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Superior document: | Frontiers in microbiology |
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Place / Publishing House: | [Place of publication not identified] : : Frontiers Media SA,, 2015. ©2007-2015 |
Year of Publication: | 2015 |
Language: | English |
Series: | Frontiers in microbiology.
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Physical Description: | 1 online resource (173 pages) :; illustrations; digital, PDF file(s). |
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Tomoyuki Miura auth Animal model studies on viral infections [electronic resource] / Topic editors: Akio Adachi and Tomoyuki Miura. Frontiers Media SA 2015 [Place of publication not identified] : Frontiers Media SA, 2015. ©2007-2015 1 online resource (173 pages) : illustrations; digital, PDF file(s). text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Frontiers research topics Frontiers in microbiology Includes bibliographical references. Open access Unrestricted online access star Animal model studies on viral infections --Animal models for human Herpesvirus 6 infection --Animal models for Ebola and Marburg virus infections --Hepatitis C virus infection and related liver disease: the quest for the best animal model --Can non-human primates serve as models for investigating Dengue disease pathogenesis? --A transgenic mouse model of human T cell Leukemia virus type-1 associated diseases --Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus --Macaques as model hosts for studies of HIV-1 infection --Macaque-tropic Human Immunodeficiency Virus type 1: breaking out of the host restriction factors --Genetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic Simian-Human Immunodeficiency Virus infection --A novel but simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4⁺ T cells in the hu-PBL SCID mice --Growth potentials of CCR5-Tropic/CXCR4-Tropic HIV-1mt clones in macaque cells --Sensitive detection of measles virus infection in the blood and tissues of humanized mouse by one-step quantitative RT-PCR --Quantification of viral infection dynamics in animal experiments --Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells --Increased infectivity in human cells and resistant to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail --Natural infection of murine novovirus in conventional and specific pathogen free laboratory mice --HPV18 E1̂ˆ̂E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins. Understanding viral replication and pathogenicity properties in infected individuals is a major mission of animal virology. Animal models are essential to analyze the in vivo viral characteristics and to develop countermeasures against viruses. To fight against a wide variety of viruses, basic studies with specific and/ or common approaches are required. This Research Topic collects articles that describe studies on numerous virus species at various stages toward animal experiments: (i) description/evaluation/ new challenges of animal model studies; (ii) experimental material/methods for animal model studies; (iii) observations for upcoming animal model studies. Numbers of DNA and RNA viruses such as HHV-6, HPV, Ebola virus, HCV, dengue virus, HTLV-1, HIV-1, SIV, and measles virus are covered by this special issue consisting of original research, methods, review, mini-review, and opinion articles. All readers would understand, we believe and hope, that animal model studies are critical for current virology as always. Description based on e-publication, viewed on July 12, 2018. English Microbiology. Virus diseases Pathogenesis. Virology Research. viral replication animal models viral infections anti-viral strategies viral pathogenicity Adachi, Akio, editor. Miura, Tomoyuki, editor. 2-88919-456-6 Frontiers in microbiology. |
language |
English |
format |
Electronic eBook |
author |
Tomoyuki Miura |
spellingShingle |
Tomoyuki Miura Animal model studies on viral infections Frontiers research topics Frontiers in microbiology Animal model studies on viral infections --Animal models for human Herpesvirus 6 infection --Animal models for Ebola and Marburg virus infections --Hepatitis C virus infection and related liver disease: the quest for the best animal model --Can non-human primates serve as models for investigating Dengue disease pathogenesis? --A transgenic mouse model of human T cell Leukemia virus type-1 associated diseases --Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus --Macaques as model hosts for studies of HIV-1 infection --Macaque-tropic Human Immunodeficiency Virus type 1: breaking out of the host restriction factors --Genetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic Simian-Human Immunodeficiency Virus infection --A novel but simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4⁺ T cells in the hu-PBL SCID mice --Growth potentials of CCR5-Tropic/CXCR4-Tropic HIV-1mt clones in macaque cells --Sensitive detection of measles virus infection in the blood and tissues of humanized mouse by one-step quantitative RT-PCR --Quantification of viral infection dynamics in animal experiments --Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells --Increased infectivity in human cells and resistant to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail --Natural infection of murine novovirus in conventional and specific pathogen free laboratory mice --HPV18 E1̂ˆ̂E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins. |
author_facet |
Tomoyuki Miura Adachi, Akio, Miura, Tomoyuki, |
author_variant |
t m tm |
author2 |
Adachi, Akio, Miura, Tomoyuki, |
author2_variant |
a a aa t m tm |
author2_role |
TeilnehmendeR TeilnehmendeR |
author_sort |
Tomoyuki Miura |
title |
Animal model studies on viral infections |
title_full |
Animal model studies on viral infections [electronic resource] / Topic editors: Akio Adachi and Tomoyuki Miura. |
title_fullStr |
Animal model studies on viral infections [electronic resource] / Topic editors: Akio Adachi and Tomoyuki Miura. |
title_full_unstemmed |
Animal model studies on viral infections [electronic resource] / Topic editors: Akio Adachi and Tomoyuki Miura. |
title_auth |
Animal model studies on viral infections |
title_new |
Animal model studies on viral infections |
title_sort |
animal model studies on viral infections |
series |
Frontiers research topics Frontiers in microbiology |
series2 |
Frontiers research topics Frontiers in microbiology |
publisher |
Frontiers Media SA Frontiers Media SA, |
publishDate |
2015 |
physical |
1 online resource (173 pages) : illustrations; digital, PDF file(s). |
contents |
Animal model studies on viral infections --Animal models for human Herpesvirus 6 infection --Animal models for Ebola and Marburg virus infections --Hepatitis C virus infection and related liver disease: the quest for the best animal model --Can non-human primates serve as models for investigating Dengue disease pathogenesis? --A transgenic mouse model of human T cell Leukemia virus type-1 associated diseases --Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus --Macaques as model hosts for studies of HIV-1 infection --Macaque-tropic Human Immunodeficiency Virus type 1: breaking out of the host restriction factors --Genetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic Simian-Human Immunodeficiency Virus infection --A novel but simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4⁺ T cells in the hu-PBL SCID mice --Growth potentials of CCR5-Tropic/CXCR4-Tropic HIV-1mt clones in macaque cells --Sensitive detection of measles virus infection in the blood and tissues of humanized mouse by one-step quantitative RT-PCR --Quantification of viral infection dynamics in animal experiments --Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells --Increased infectivity in human cells and resistant to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail --Natural infection of murine novovirus in conventional and specific pathogen free laboratory mice --HPV18 E1̂ˆ̂E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins. |
isbn |
2-88919-456-6 |
illustrated |
Illustrated |
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hierarchy_parent_title |
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Animal model studies on viral infections |
container_title |
Frontiers in microbiology |
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