Hedgehog Signaling in Organogenesis and Tumor Microenvironment

Hedgehog Signaling in Organogenesis and Tumor Microenvironment

The Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with...

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Shimo, Tsuyoshi
Year of Publication:2020
Language:English
Physical Description:1 electronic resource (172 p.)
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spelling Shimo, Tsuyoshi edt
Hedgehog Signaling in Organogenesis and Tumor Microenvironment
Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
1 electronic resource (172 p.)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
The Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with neoplastic transformation, cancer cell proliferation, metastasis, multiple cancers’ drug resistance, and survival rates. This book focuses on several aspects of Hedgehog signaling in organogenesis and the tumor microenvironment, and presents reviews and original papers on recent efforts in the field of Hedgehog signaling.
English
Medicine bicssc
Cyp26 enzymes
congenital anomalies
CRE/LoxP
hedgehog signaling
mouse models
retinoic acid
smoothened
sonic hedgehog
sonic hedgehog (SHH)
oral squamous cell carcinoma (OSCC)
tumor microenvironment (TME)
tumor-associated macrophages (TAMs)
cancer-associated fibroblasts (CAFs)
tumor-associated angiogenesis
hedgehog
growth plate
endochondral ossification
chondrocyte
osteoblast
bone disease
TMJ
synovial joint
articular disc
Ihh
PTHrP
osteoarthritis
epithelial-mesenchymal interaction (EMI)
prostate cancer
external genitalia
androgen
basement membrane
bone morphogenetic protein
stem cell
animal experiment
fracture healing
cancer stem cells
hypospadias
urethra
penis
bone
hedgehog signalling
tooth development
epithelial and mesenchymal interaction
Gli1
mesenchymal stem cell
lineage tracing analysis
stem cell marker
3-03936-260-7
3-03936-261-5
Shimo, Tsuyoshi oth
language English
format eBook
author2 Shimo, Tsuyoshi
author_facet Shimo, Tsuyoshi
author2_variant t s ts
author2_role Sonstige
title Hedgehog Signaling in Organogenesis and Tumor Microenvironment
spellingShingle Hedgehog Signaling in Organogenesis and Tumor Microenvironment
title_full Hedgehog Signaling in Organogenesis and Tumor Microenvironment
title_fullStr Hedgehog Signaling in Organogenesis and Tumor Microenvironment
title_full_unstemmed Hedgehog Signaling in Organogenesis and Tumor Microenvironment
title_auth Hedgehog Signaling in Organogenesis and Tumor Microenvironment
title_new Hedgehog Signaling in Organogenesis and Tumor Microenvironment
title_sort hedgehog signaling in organogenesis and tumor microenvironment
publisher MDPI - Multidisciplinary Digital Publishing Institute
publishDate 2020
physical 1 electronic resource (172 p.)
isbn 3-03936-260-7
3-03936-261-5
illustrated Not Illustrated
work_keys_str_mv AT shimotsuyoshi hedgehogsignalinginorganogenesisandtumormicroenvironment
status_str n
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carrierType_str_mv cr
is_hierarchy_title Hedgehog Signaling in Organogenesis and Tumor Microenvironment
author2_original_writing_str_mv noLinkedField
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