Hedgehog Signaling in Organogenesis and Tumor Microenvironment
The Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with...
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| Year of Publication: | 2020 |
| Language: | English |
| Physical Description: | 1 electronic resource (172 p.) |
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| 245 | 1 | 0 | |a Hedgehog Signaling in Organogenesis and Tumor Microenvironment |
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| 520 | |a The Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with neoplastic transformation, cancer cell proliferation, metastasis, multiple cancers’ drug resistance, and survival rates. This book focuses on several aspects of Hedgehog signaling in organogenesis and the tumor microenvironment, and presents reviews and original papers on recent efforts in the field of Hedgehog signaling. | ||
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| 653 | |a oral squamous cell carcinoma (OSCC) | ||
| 653 | |a tumor microenvironment (TME) | ||
| 653 | |a tumor-associated macrophages (TAMs) | ||
| 653 | |a cancer-associated fibroblasts (CAFs) | ||
| 653 | |a tumor-associated angiogenesis | ||
| 653 | |a hedgehog | ||
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| 653 | |a synovial joint | ||
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| 653 | |a tooth development | ||
| 653 | |a epithelial and mesenchymal interaction | ||
| 653 | |a Gli1 | ||
| 653 | |a mesenchymal stem cell | ||
| 653 | |a lineage tracing analysis | ||
| 653 | |a stem cell marker | ||
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