A master regulator of oxidative stress : : the transcription factor Nrf2 / / edited by Jose Antonio Morales-Gonzalez, Ángel Morales-González, Eduardo Osiris Madrigal-Santillan.
Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. The...
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| Place / Publishing House: | Rijeka, Croatia : : IntechOpen,, [2016] ©2016 |
| Year of Publication: | 2016 |
| Language: | English |
| Physical Description: | 1 online resource (210 pages) :; illustrations |
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| 100 | 1 | |a Jose Antonio Morales-Gonzalez |4 auth | |
| 245 | 0 | 2 | |a A master regulator of oxidative stress : |b the transcription factor Nrf2 / |c edited by Jose Antonio Morales-Gonzalez, Ángel Morales-González, Eduardo Osiris Madrigal-Santillan. |
| 246 | |a Master regulator of oxidative stress | ||
| 246 | |a A Master Regulator of Oxidative Stress â The Transcription Factor Nrf2 | ||
| 260 | |b IntechOpen |c 2016 | ||
| 264 | 1 | |a Rijeka, Croatia : |b IntechOpen, |c [2016] | |
| 264 | 4 | |c ©2016 | |
| 300 | |a 1 online resource (210 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 588 | |a Description based on: online resource; title from PDF information screen (InTech, viewed October 17, 2022). | ||
| 504 | |a Includes bibliographical references. | ||
| 506 | |a Open access |f Unrestricted online access |2 star | ||
| 520 | |a Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways. | ||
| 546 | |a English | ||
| 650 | 0 | |a Transcription factors. | |
| 653 | |a Life Sciences | ||
| 653 | |a Molecular Biology | ||
| 653 | |a Genetics and Molecular Biology | ||
| 653 | |a Biochemistry | ||
| 776 | |z 953-51-2837-X | ||
| 700 | 1 | |a Morales-Gonzalez, Jose Antonio, |e editor. | |
| 700 | 1 | |a Morales-González, Ángel , |e editor. | |
| 700 | 1 | |a Madrigal-Santillan, Eduardo Osiris, |e editor. | |
| 906 | |a BOOK | ||
| ADM | |b 2023-06-10 04:38:26 Europe/Vienna |f system |c marc21 |a 2019-04-13 22:04:18 Europe/Vienna |g false | ||
| AVE | |i DOAB Directory of Open Access Books |P DOAB Directory of Open Access Books |x https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5351637350004498&Force_direct=true |Z 5351637350004498 |b Available |8 5351637350004498 | ||