The Construction of Analogy-Based Research Programs : : The Lock-and-Key Analogy in 20th Century Biochemistry /

The Construction of Analogy-Based Research Programs : : The Lock-and-Key Analogy in 20th Century Biochemistry / / Rebecca Mertens.

When the German chemist Emil Fischer presented his key-lock hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical struc...

Full description

Saved in:
Bibliographic Details
Superior document:Title is part of eBook package: De Gruyter DG Plus PP Package 2019 Part 2
VerfasserIn:
Mertens, Rebecca,
Place / Publishing House:Bielefeld : : transcript Verlag, , [2019]
©2019
Year of Publication:2019
Language:English
Series:Science Studies
Online Access:
Physical Description:1 online resource (224 p.)
Tags: Add Tag
No Tags, Be the first to tag this record!
Table of Contents:
  • Frontmatter
  • Table of contents
  • Preface
  • 1 The lock-and-key analogy and its influence on 20th century biochemistry
  • 2 The lock-and-key analogy in Emil Fischer's program on sugar fermentation, 1890-1907
  • 3 The making of the lock-and-key model of the antibody-antigen relationship, 1886-1930
  • 4 Lock-and-key foundations for molecular biology: Linus Pauling and the Caltech group, 1930-1960
  • 5 Lock-and-key-based modeling and its influence on the development of biochemical research programs
  • 6 Concluding remarks on the construction of analogy-based research programs
  • Literature

Similar Items