Table of Contents: Theoretical Drug Design Methods /

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Bibliographic Details
Superior document:	Title is part of eBook package: De Gruyter ABA STEM - 1971 - 1990
VerfasserIn:	Franke, Rainer,
Place / Publishing House:	Berlin ;, Boston : : De Gruyter, , [1984] Akademie-Verlag Berlin, , [1984] ©1984
Year of Publication:	1984
Edition:	rev., ext. English transl. of ,,Optimierungsmethoden in der Wirkstofforschung. Quantitative Struktur-Wirkungs-Analyse“, publ. 1980 as ,,Sonderband 2“ in the series ,,Beitrage zur Forschungstechnologie“., Reprint 2024
Language:	English
Online Access:	https://doi.org/10.1515/9783112706992 https://www.degruyter.com/isbn/9783112706992 Cover
Physical Description:	1 online resource (415 p.) :; With 44 Figures and 88 Tables
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Table of Contents:

Frontmatter
Contents
1. Introduction and Formulation of Problems
2. Measures of Biological Activity A
3. Extrathermodynamic Approach to Quantitative Structure-Activity Analysis (Hansch Analysis)
4. Hydrophobic Effects on Biological Activity: the Function fn(xh)
5. Electronic Influences on Biological Activity: the Function fn(xh)
6. Steric Effects on Biological Activity: the Function fn(xh)
7. Interrelations of Molecular Parameters and the Collinearity Problem
8. Practical Aspects of Quantitative Structure-Activity Analysis by the Extrathermodynamic Approach (Hansch Analysis)
9. Other Approaches to Quantitative Structure-Activity Analysis with Extrathermodynamic Molecular Parameters
10. Non-Computer-Assisted Search Operations on the Basis of the Extrathermodynamic Approach
11. Procedures with Structural Parameters
12. Receptor Mapping and Pharmacophores
13. Response Profiles
14. Concluding Remarks
15. Appendix: Some Principles of Linear Regression Analysis
16. Index