Theoretical Drug Design Methods / / Rainer Franke.

• Superior document: Title is part of eBook package: De Gruyter ABA STEM - 1971 - 1990
• VerfasserIn: Franke, Rainer,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [1984]; Akademie-Verlag Berlin, , [1984]; ©1984
• Year of Publication: 1984
• Edition: rev., ext. English transl. of ,,Optimierungsmethoden in der Wirkstofforschung. Quantitative Struktur-Wirkungs-Analyse“, publ. 1980 as ,,Sonderband 2“ in the series ,,Beitrage zur Forschungstechnologie“., Reprint 2024
• Language: English
• Physical Description: 1 online resource (415 p.) :; With 44 Figures and 88 Tables
• Other title: Frontmatter --; Contents --; 1. Introduction and Formulation of Problems --; 2. Measures of Biological Activity A --; 3. Extrathermodynamic Approach to Quantitative Structure-Activity Analysis (Hansch Analysis) --; 4. Hydrophobic Effects on Biological Activity: the Function fn(xh) --; 5. Electronic Influences on Biological Activity: the Function fn(xh) --; 6. Steric Effects on Biological Activity: the Function fn(xh) --; 7. Interrelations of Molecular Parameters and the Collinearity Problem --; 8. Practical Aspects of Quantitative Structure-Activity Analysis by the Extrathermodynamic Approach (Hansch Analysis) --; 9. Other Approaches to Quantitative Structure-Activity Analysis with Extrathermodynamic Molecular Parameters --; 10. Non-Computer-Assisted Search Operations on the Basis of the Extrathermodynamic Approach --; 11. Procedures with Structural Parameters --; 12. Receptor Mapping and Pharmacophores --; 13. Response Profiles --; 14. Concluding Remarks --; 15. Appendix: Some Principles of Linear Regression Analysis --; 16. Index
• Format: Mode of access: Internet via World Wide Web.
• ISBN: 9783112706992; 9783111252315; 9783111252957
• DOI: 10.1515/9783112706992
• Access: restricted access
• Hierarchical level: Monograph
• Statement of Responsibility: Rainer Franke.