Unconjugated pterins and related biogenic amines : : proceedings of the First International Workshop, Flims, Switzerland, february 28 - march 7, 1987 / / hrsg. von Hans-Christoph Curtius, 1987, Flims› Workshop on Unconjugated Pterins and Related Biogenic Amines ‹1.

• Superior document: Title is part of eBook package: De Gruyter DGBA Reference Works <1990
• MitwirkendeR: Andondonskaja-Renz, B.,; Andre, S.,; Antoulas, S.,; Bacher, A.,; Biasetti, S.,; Blau, N.,; Bonetti, G.,; Bosshard, R.,; Bracco, G.,; Bräutigam, M.,; Cotton, R. G. H.,; Cotton, R.G.H.,; Curtius, H.-Ch.,; Curtius, H.Ch.,; Curtius, Hans-Christoph,; DHONDT, J.L.,; DHONDT, Jean-Louis,; Dahinden, R.,; Dahl, H.-H.M.,; Danks, D.M.,; Demtröder, Κ.,; Dhondt, J.L.,; Dianzani, I.,; Dorche, C.,; Eisenreich, W.,; FARRIAUX, J.P.,; FORZY, G.,; Ferraris, S.,; Ferré, J.,; Fink, M.,; Floss, H. G.,; Fontana, Adriano,; Forzy, G.,; Ghisla, S.,; Goldberg, Μ.,; Guardamagna, O.,; Guibaud, P.,; HAYTE, J.M.,; Hasegawa, H.,; Hasler, Th.,; Hayte, J.M.,; Herold, M.,; Huber, Ch.,; Huber, Christoph,; Hutchison, W.M.,; Höniges, Ε.,; Iavarone, A.,; Ichiyama, A.,; Jennings, I. G.,; Jennings, I.G.,; Kaiser, A.,; Keller, P. J.,; Kierat, L.,; Koch, Μ.A.,; Kolb, H.J.,; Kuhn, D.M.,; Kunze, R.O.F.,; Kuster, Th.,; LARGILLIERE, C.,; Le Van, Q.,; Lehmann, H.,; Leimbacher, W.,; Leone, L.,; Leupold, D.,; Levine, Robert A.,; Levis, F.,; Matasovic, A.,; McAdam, W.,; McAdam, W.J.,; Meinschad, Ch.,; Milstien, Sheldon,; Naylor, E.W.,; Neuheiser, F.,; Niederwieser, A.,; Niederwieser, Alois,; Nilsson, K.,; Nüssler, V.,; Ozalp, I.,; Pagliardini, S.,; Parniak, Michael A.,; Pfister, K.,; Pfleiderer, W.,; Ponzone, A.,; Przybylski, M.,; Raschdorf, F.,; Redweik, U.,; Richter, W.J.,; Rokos, H.,; Rokos, K.,; Rolland, M.O.,; Schoedon, G.,; Schoedon, Gabriele,; Schwarzkopf, B.,; Seidl, J.,; Smith, S.,; Staudenmann, W.,; Steinerstauch, P.,; Takikawa, Sh.-I.,; Troppmair, J.,; Troppmair, Jacob,; Viscontini, M.,; Wake, S.,; Zagalak, B.,; Zeitler, H.-J.,; Ziegler, I.,; Ziegler, Irmgard,
• HerausgeberIn: Curtius, Hans-Christoph,; Workshop on Unconjugated Pterins and Related Biogenic Amines ‹1, 1987, Flims›,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2011]; ©1987
• Year of Publication: 2011
• Edition: Reprint 2011
• Language: German
• Physical Description: 1 online resource (397 p.) :; Num figs.

Table of Contents

I-VI -- PREFACE -- ACKNOWLEDGEMENTS -- CONTENTS -- In Memoriam ALOIS NIEDERWIESER (1935 - 1987) -- SECTION A: CHEMISTRY AND ANALYSIS OF PTERINS -- HOMOGENEOUS CATALYTIC HYDROGENATION OF L-BIOPTERIN: INFLUENCE OF THE CHIRALITY OF THE SIDE CHAIN AND THE CATALYST ON ITS DIASTEREOSELECTIVE INDUCTION -- SYNTHESIS OF D-NEOPTERIN-3'-PHOSPHATES -- 5-ALKYL-5.6.7.8-TETRAHYDROBIOPTERINS -- MASS SPECTROMETRIC INVESTIGATIONS OF PTERIDINES -- THE STRUCTURAL CHARACTERIZATION OF 6-PYRUVOYL TETRAHYDROPTERIN BY FAST ATOM BOMBARDMENT MASS SPECTROMETRY WITH ONE- AND TWO-DIMENSIONAL MASS ANALYSIS (FAB/MS AND FAB/MSMS) -- SECTION Β: BIOCHEMISTRY AND METABOLISM OF PTERINS -- TETRAHYDROBIOPTERIN: OTHER PHYSIOLOGICAL ROLES IN ADDITION TO AROMATIC AMINO ACID HYDROXYLATION? -- 1H-NMR STUDIES WITH TETRAHYDROBIOPTERINS, EVIDENCE FOR THE STRUCTURE OF 6-PYRUVOYLTETRAHYDROPTERIN, AN INTERMEDIATE IN THE BIOSYNTHESIS OF TETRAHYDROBIOPTERIN -- PURIFICATION OF 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE FROM SALMON LIVER -- PURIFICATION OF 6-PYRUVOYL TETRAHYDROPTERIN 2'-KETO REDUCTASE FROM HUMAN LIVER -- HUMAN GTP CYCLOHYDROLASE I: PURIFICATION AND PREPARATION OF MONOCLONAL ANTIBODIES -- DIHYDROMONAPTERIN TRIPHOSPHATE: OCCURRENCE, ANALYSIS, AND EFFECT ON TETRAHYDROBIOPTERIN BIOSYNTHESIS in vivo AND in vitro -- BIOSYNTHESIS OF PTERIDINES AND DEAZA FLAVINS IN METHANOGENIC BACTERIA -- TETRAHYDROBIOPTERIN BIOSYNTHESIS AND PTERIDINE METABOLISM IN CELLS OF THE BLOOD SYSTEM, LYMPHOID TISSUES AND IN BIOLOGICAL FLUIDS -- MODIFIED PTERIPINE SYNTHESIS IN TRANSFORMED CELL LINES AND DURING HEAT SHOCK -- DISEASE ASSOCIATED ALTERATIONS OF PTERIN BIOSYNIHESIS: ENHANCEMENT IN INFLAMMATORY DISEASE, HEMOPOIETIC REGENERATION AND ENDOTOXINEMIA -- METABOLISM OF PTERINS IN THE CELLULAR IMMUNE SYSTEM OF MAN AND MOUSE -- TETRAHYDROBIOPTERIN SYNTHESIS IS TRIGGERED BY INTERLEUKIN 2 BINDING AND MODULATES RECEPTOR AFFINITY -- KINETICS OF PRODUCTION AND RELEASE OF NEOPTERIN. COMPARISON OF HUMAN PBMC WITH THE PERMANENT MONOCYTIC CELL LINE U937 AND ITS SUBCLONES. -- SECTION D: PTERINS IN DIFFERENT DISEASES -- VARIATIONS OF NEOPTERIN, DIHYDRONEOPTERIN AND IMMUNOLOGICAL PARAMETERS DURING PHYSICAL EXERCISE (JOGGING) -- BIOPTERIN AND NEOPTERIN IN PLASMA AND LYMPHO-MONONUCLEAR BIOPTERIN IN GRAFT VERSUS HOST DISEASE AND INFECTION AFTER BONE MARROW TRANSPLANTATION. -- EFFECTS OF ΡIRENZEPINE, ACICLOVIR AND TRIMETHOPRIM ON PTERINS IN BLOOD CELLS AND PLASMA -- SECTION Ε: TETRAHYDROBIOPTERIN DEFICIENCIES -- HETEROGENEITY OF TETRAHYDROBIOPTERIN DEFICIENCY -- PRENATAL DIAGNOSIS OF TETRAHYDROBIOPTERIΝ DEFICIENCY -- SEPIAPTERIN REDUCTASE IN HUMAN AMNIOCYTES, SKIN FIBROBLASTS, CHORIONIC VILLI AND STIMULATED MONONUCLEAR BLOOD CELLS. -- IMPAIRED BIOPTERIN SYNTHESIS IN A PATIENT WITH MILD HYPERPHENYLALANINEMIA. A NEW VARIANT ? -- DIHYDROPTERIDINE REDUCTASE ACTIVITY IN FETAL TISSUES -- MOLECULAR ANALYSIS OF HUMAN DIHYDROPTERIDINE REDUCTASE AND DIHYDROPTERIDINE REDUCTASE DEFICIENCY -- FATE OF PERIPHERALLY ADMINISTERED TETRAHYDROBIOPTERIΝ IN CONGENITAL TETRAHYDROBIOPTERIΝ DEFICIENCY -- 6-PYRUVOYL-TETRAHYDROPTERIN SYNTHASE DEFICIENCY: THERAPEUTIC TRIAL WITH TWO DIFFERENT SYNTHETIC PTERIN ANALOGUES IN THREE PATIENTS -- PLACENTAL BARRIER IN MOTHER-TO-FETUS TRANSFER OF TETRAHYDROBIOPTERIN IN HUMANS -- SECTION F: MONOAMINE NEUROTRANSMITTERS AND ENZYMES -- THERAPEUTIC POTENTIAL OF TETRAHYDROBIOPTERIN THERAPY IN NEUROLOGICAL AND PSYCHIATRIC ILLNESS -- ORGANIZATION OF THE CATALYTIC AND REGULATORY SITES OF RAT LIVER PHENYLALANINE HYDROXYLASE -- IMMUNOCHEMICAL STUDIES OF PHENYLALANINE HYDROXYLASE -- INFLUENCE OF SUBSTRATES AND COFACTORS ON TYROSINE HYDROXYLASE -- MECHANISM OF ACTIVATION OF TRYPTOPHAN 5-MONOOXYGENASE BY MERCAPTIDES -- EFFECTS OF TETRAHYDROPTERINS ON DOPA PRODUCTION IN VITRO AND IN VIVO -- PTERINS AND MONOAMINE METABOLITES IN CEREBROSPINAL FLUID -- AUTHOR INDEX -- SUBJECT INDEX -- LIST OF PARTICIPANTS