Concepts in Vaccine Development / / ed. by Stefan H. E. Kaufmann.

• Superior document: Title is part of eBook package: De Gruyter DGBA Medicine and Life Sciences 1990 - 1999
• MitwirkendeR: Alexander, Jeff,; Amador, Roberto,; Ashley, Robert V.,; Bogdan, Christian,; Bretscher, Peter,; Capron, André,; Chesnut, Robert W.,; Cohen, Irun R.,; Cole, Geoffrey A.,; Covacci, Antonello,; Cox, John,; Czerkinsky, Cecil,; Dittmann, Sieghart,; Doherty, Peter C.,; Donnelly, John J.,; Ewald, Paul W.,; Gander, Bruno,; Ghiara, Paolo,; Grey, Howard M.,; Heilman, Carole,; Holmgren, Jan,; Hormaeche, Carlos E.,; Kaufmann, Stefan H. E.,; Kaufmann, Stefan H.E.,; Kersten, Gideon F.A.,; Khan, C. M. Anjam,; Klein, David L.,; Kubo, Ralph T.,; Kurth, Reinhard,; Liu, Margaret A.,; Lövgren-Bengtsson, Karin,; Mor, Felix,; Morein, Bror,; Murray, Christopher J. L.,; Norley, Stephen,; Paoletti, Enzo,; Patarroyo, Manuel E.,; Perkus, Marion E.,; Pizza, Mariagrazia,; Rammensee, Hans-Georg,; Rappuoli, Rino,; Riveau, Gilles J.,; Röllinghoff, Martin,; Schild, Hansjörg,; Sette, Alessandro,; Shiver, John W.,; Sidney, John,; Sun, Jia-Bin,; Svennerholm, Ann-Mari,; Szalay, Gudrun,; Telford, John L.,; Ulmer, Jeffrey B.,; Wentworth, Peggy A.,; Woodland, David L.,
• HerausgeberIn: Kaufmann, Stefan H. E.,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2012]; ©1996
• Year of Publication: 2012
• Edition: Reprint 2012
• Language: English
• Physical Description: 1 online resource (583 p.)

Table of Contents

Frontmatter -- Preface -- Bicentennial of the first vaccination by Edward Jenner -- Contents -- 1. The Need for New Vaccines -- 1.1. Vaccines as Evolutionary Tools: The Virulence-Antigen Strategy -- 1.2. Economic Perspectives on Vaccine Needs -- 1.3. Future Immunization Strategies – Considerations from the Public Health View -- 1.4. The New Pertussis Vaccines -- 2. General Principles of Immunology -- 2.1. Basic Principles of Immunity Against Intracellular Bacteria and Protozoa -- 2.2. Viral Immunity and Vaccine Strategies -- 2.3. Broadly Reactive HLA Restricted Τ Cell Epitopes and Their Implications for Vaccine Design -- 2.4. Quantitative Considerations in the Design of Vaccination Strategies Against Pathogens Uniquely Susceptible to Cell-Mediated Attack -- 2.5. The Impact of the Type 1 and Type 2 Τ Helper Cell Concept on Novel Vaccine Design with Emphasis on Protection Against Leishmania Parasites -- 3. General Principles of Vaccinology -- 3.1. Modern Adjuvants. Functional Aspects -- 3.2. Biodegradable Microspheres as Vehicles for Antigens -- 3.3. Peptide Based Vaccines -- 3.4. Recombinant Bacteria as Vaccine Carriers of Heterologous Antigens -- 3.5. Genetic Detoxification of Bacterial Toxins -- 3.6. Recombinant Virus as Vaccination Carrier of Heterologous Antigens -- 3.7. Naked DNA Vaccination -- 3.8. Oral Vaccination, Mucosal Immunity and Oral Tolerance with Special Reference to Cholera Toxin -- 4. Specific Vaccination Strategies -- 4.1. Helicobacter pylori: Pathogenic Determinants and Strategies for Vaccine Design -- 4.2. Malaria Vaccination -- 4.3. Vaccination Against Schistosomiasis: Concepts and Strategies -- 4.4. AIDS Vaccination -- 4.5. Vaccination Therapy Against Autoimmune Diseases -- Contributors -- Index