Fibrinogen. Proceedings/ Workshop on Fibrinogen. / Vol. 4, : Fibrin formation and Fibrinolysis ; April, 2–3, 1985, London, England / / hrsg. von D. A. Lane.
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Table of Contents:
- Frontmatter
- Preface
- Contributors
- Contents
- I. Synthesis And Assembly
- A scheme for the intracellular assembly of human fibrinogen
- Evidence that platelet and plasma fibrinogen have the same A-alpha chain gene product
- Fibrinopeptide A and the phosphorylation of fibrinogen
- II. Structure and Function
- Size and shape of the fibrinogen molecule: crystalline forms of native and modified human fibrinogen
- The C-terminal polymerisation domain of fibrinogen
- γ- Chain Crosslinking Of Fibrin At Dd-Trans Contact
- Soluble fibrin contains fibrin polymers of different molecular weight. Ultracentrifugation studies at 37°C
- Relationship of final thickness of fibrin fibers to maximal rate of assembly and to fibrinopeptide B release
- III. Congenital Variants
- Fibrinogen New York 1: The structural, functional, and genetic defects and an hypothesis of the role of fibrin in the regulation of coagulation and fibrinolysis
- Fibrinogen Pontoise - a genetically abnormal fibrinogen with defective fibrin polymerisation but normal fibrinopeptide release
- Fibrinogen Milano I: Abnormal fibrin polymerization related to a carboxy-terrainal defect of the γ-chain (γ-330 Asp Val)
- Fibrinogen "Bergamo I" (Λα 16 Arg - Cys): Alternative methods for structure elucidation
- Screening small plasma samples by HPLC for abnormalities of fibrinopeptide release
- Iv. Fibrin(ogen) And Fibrinolysis
- On the role of fibrin in the fibrinolytic system
- Isolation and characterisation of plasmic degradation products of fibrinogen by high-performance liquid chromatography
- The acceleration of tissue-type plasminogen activator (t-PA)-mediated activation of plasminogen by fibrinogen cyanogen bromide fragments is species specific
- Role of fibrin polymerization in fibrinolysis: Comparison between polymerisable and unpolymerisable fibrins in the potentiating effect of plasminogen activation by tissue-type plasminogen activator (tpA)
- Role of fibrin and its degradation products in the activation of plasminogen by streptokinase and urokinase
- V. Interactions With Cells
- The role of fibrinogen in platelet aggregation
- Platelet-associated fibrinogen: Conformational change of fibrinogen induced by its adsorption to platelet-surface
- Migration of cultured endothelial cells in response to fibrinogen
- Characteristics of the interactions of fibrinogen and soluble fibrin with cultured endothelial cells
- Mechanism of fibrin-induced disorganisation of cultured human endothelial cells
- The fibrinogen: red cell interaction and its influence on blood rheology
- Haemorheologic effects of plasmin and thrombininduced fibrinogen derivatives: An in vitro study
- Binding of human fibrinogen to streptococci and its role in streptococcal pathogenicity
- VI. Assays To Fibrin(ogen) Fragments And Their Use
- Discrimination between fibrin and fibrinogen by a monoclonal antibody against a synthetic hexapeptide representing the amino-terminus of the alpha-chain of fibrin
- A new enzyme immunoassay of fibrin(ogen) degradation products in plasma using a monoclonal antibody
- Fibrin(ogen) degradation products. Determination using a monoclonal anti D neo antibody. Advantages in clinical investigation
- A monoclonal antibody, specific for human fibrinogen and fibrinopeptide A-containing fragments. Its application in an enzyme-immunoassay for fibrinogen degradation products, suitable for use in plasma
- A monoclonal antibody against the CNBr-peptide F-CB3 of the Aα-chain of human fibrinogen
- Clinical aspects of fibrin formation and fibrinolysis measured with monoclonal antibodies against D-dimer
- Fibrinogen derivatives in acute stroke
- VII. Fibrin(ogen) And Disease Pathology
- Triggering of the extrinsic blood coagulation system
- Extravascular fibrin formation and fibrinolysis in a model of inflammation accompanying cellular hypersensitivity
- Extra-vascular fibrin deposition in cellular hypersensitivity - the role of T lymphocyte-macrophage interactions
- Fibrinolytic studies in disorders of connective tissue
- Soluble fibrin/fibrinogen related antigen in human intima in relation to atherogenesis
- Fibrinogen as a possible risk factor for IHD in the Caerphilly study
- VIII. Appendix: Data On Fibrinogen
- Fibrinogen amino acid sequences
- Author Index
- Subject Index
- Backmatter
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