The Roots of Modern Biochemistry : : Fritz Lippmann's Squiggle and its Consequences / / ed. by Hans von Döhren, Horst Kleinkauf, Lothar Jaenicke.
“The Roots of Modern Biochemistry is a superb introduction into modern biochemistry, much recommended as initial overview of the subject.” Prof. Dr. Hans Fritz, Ludwig-Maximilians-University Munich
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Table of Contents:
- I-VI
- Preface
- Contents
- 1. Fritz Lipmann (1899-1986)
- 1. Fritz Lipmann (1899-1986)
- Life with Fritz
- A Long Life in Times of Great Upheaval
- Fritz Lipmann: In Memoriam
- Lipmann's Remarkably Fulfilled Life as a Researcher
- Fritz Lipmann: June 12, 1899 - July 24, 1986
- Fritz Lipmann Molding the Design of Molecular Bioenergetics
- Recollections of Fritz Lipmann, 1941-1945
- In Celebration of the Scientific Genius of Fritz Lipmann
- Lipmann and "Not Strictly Biochemistry"
- Communication in Metabolic Control Intuition and Method in Biochemistry: Four Years each with Krebs and Lipmann
- Fritz Lipmann: Squiggle to Protein Sulfation
- Fritz Lipmann (1899-1986), Honorary Member of the Leopoldina Academy
- Dahlem in the Late Nineteen Twenties
- Our Apprenticeship
- The Kaiser-Wilhelm-Institutes in Berlin-Dahlem in the Late 1930ies and Early 1940ies: Reminiscences of a Student of Biochemistry
- On the Origin of the Squiggle (~)
- 2. Biochemistry Comes of Age
- 2. Biochemistry Comes of Age
- The History of Metabolites Isolated from Urine
- The Pentose Phosphate Pathway
- Glycolysis and the Dawn of Modern Biochemistry
- Energy-Rich Bonds and Enzymatic Peptide Synthesis
- A Nostalgic View of the TCA Cycle in Bacteria
- The Role of Vitamins and their Carrier Proteins in Citrate Fermentation
- Lipmann's Influence on Firefly Luminescence
- Sulfur in Biomimetic Peptide Syntheses
- The Function of Teichoic Acids in Walls and Membranes of Bacteria
- The Amidotransferases: Origins of the Concept of Affinity Labeling of Enzymes
- Intracellular Protein Degradation: Past, Present and Future
- Lipmann's Squiggle and the Unification of Cellular Structure and Function
- The Historical Intermingling of Biochemistry and Cell Biology
- Regulation of Function of Membrane Proteins by Phosphorylation and Dephosphorylation
- Molecular Biology of Brain Peptides and their Cognate Receptors
- The Biological Activity of Tuftsin, Thr-Lys-Pro-Arg
- Biosynthesis of Linear Gramicidin, Pentadeca Peptide, is Tight Linked to Serine Metabolism and to Membranous Phosphoglyceride
- From Phosphoenolpyruvate Carboxykinase to Sporulation: Personal Reflections on Dr. F. Lipmann
- Research on Nonribosomal Systems: Biosynthesis of Peptide Antibiotics
- Metabolism of Carnosine and Related Peptides
- 3. Molecular Biology Sharpens its Tools
- 3. Molecular Biology Sharpens its Tools
- DNA Repair in Human Cells: Molecular Cloning of cDNAS Coding for Enzymes Related to Repair
- Acyl ~ Phosphate Intermediates in Oxidative DNA Sugar Damage by Antibiotics
- Rts1: A Multiphenotypic, Unusual Temperature Sensitive Drug Resistance Factor
- The Partial Dependency of Human Prostatic Growth Factor on Steroid Hormones in Stimulating Thymidine Incorporation into DNA
- Developmentally Regulated Gene Amplification in Rhynchosciara
- Fritz Lipmann, a Few Personal Memories, and: What Else Came Out of the High-Energy Phosphate Bond?
- Regulation of Gene Expression by Posttranslational Modification of Transcription Factors
- How Does the Arginine Repressor Regulate the Synthesis of Arginine Biosynthetic Enzymes?
- The Biochemistry and Molecular Biology of the Terminal Reactions of Methionine Biosynthesis in Escherichia coli
- The Wheat Embryo, Then and Now
- Mechanism of Cytotoxic Action and Structures of Thiadiazolo-pyrimidines
- Architecture of Ribosomal Particles as Investigated by Image Reconstruction and X-Ray Crystallographic Studies
- Initiation of Protein Synthesis: Early Participation and Recent Revisit
- Structure of Ribosomal RNA Genes of Eukaryotes: Some Solved and Unsolved Questions
- Energetics and Dynamics of the Protein- Synthesizing Machinery
- Expression
- Punctuation in the Genetic Code: A Plausible Basis for the Degeneracy of the Code to Initiate Translation
- Reconstruction of Translation: Role of EF-P in Regulation of Peptide Bond Formation
- On the Role of Spermine in Protein Synthesis
- 4. Functional Dynamics
- 4.1 The Squiggle - Symbol of Bioenergetics
- 4.1 The Squiggle - Symbol of Bioenergetics
- Energy-Rich Compounds and Work
- Squiggle Phosphate of Inorganic Pyrophosphate and Polyphosphates
- Enzymology of 3'-Squiggled Nucleotides
- Pyridine Nucleotides as Group Transfering Coenzymes
- The Nature of Squiggle in Oxidative Phosphorylation
- Motional Dynamics of Fatty Acids: Advantages of 15N and Deuterium Substituted Fatty Acid Spin Labels for Studies of Lipid-Protein Interactions and Motion in Membrane Bilayers
- Thyroid Hormones and Oxidative Phosphorylation
- Structure-Activity Relationships of Natural and Synthetic E-β-Methoxyacrylates of the Strobilurin and Oudemansin Series
- The Intracellular Mechanism of Insulin Action
- Unity and Diversity in Biological Redox Catalysis: Comparative Enzymology of Some Microbial Oxidoreductases Showing Variation in Cofactor Identity
- Ammonia-Forming, Dissimilatory Nitrite Reductases as a Homologous Group of Hexaheme C-Type Cytochromes in Metabolically Diverse Bacteria
- Halorhodopsin
- Control of Futile Transmembrane Potassium Cycling in Escherichia coli
- Bioenergetics of Protein Transport into Mitochondria: Role of ΔΨ and of Nucleoside Triphosphates
- Some Recent Functional and Structural Contributions to the Molecular Mechanism of Photosynthesis
- Salt Toxicity and Mineral Deficiency in Plants: Cytoplasmic Ion Homeostasis, a Necessity for Growth and Survival under Stress
- 4.2 Molecular Recognition and Communication
- 4.2 Molecular Recognition and Communication
- Dawn of Ca Research: Regulation of Muscle Contraction
- Comparative Aspects of the Mechanisms of Energy Transduction in Sarcoplasmic Reticulum between Rabbit and Frog Skeletal Muscle
- Caltrin: A Versatile Regulator of Calcium Transport in Spermatozoa
- Protein Kinase C, the Structural Heterogeneity and Differential Expression in Rat Brain
- Regulation of Erythrocyte Membrane Cytoskeletal Protein Interactions by Phosphorylation
- A Kinase Splitting Membranal Proteinase: Use in the Study of Receptors Involved in the Cellular Response to Hormones
- Fritz Lipmann, Phosphoproteins and Regulation of Aromatic Amino Acid Hydroxylase Activity
- The Regulation of Hepatic Phenylalanine Hydroxylase by Phosphorylation- Dephosphorylation
- Catabolite Inactivation and Adenylate Cyclase in Yeast
- Protein Modification by Tyrosine-Sulfation: Possible Functional Implications
- Proteoglycans and Connective Tissue Pathobiochemistry
- Acylation of Myelin Proteolipid Protein: A Link to the Past
- The Unusual Regulation of the Adenylyl cyclase of Amphibian Oocytes by Progesterone - A Review
- Sterol Synergism, a Tool for Studies on Sterol Function
- Chemical Modification of Benzodiazepine Receptors of Cortical P2 Membranes
- Dual Pathways for the Catabolism of γ- Hydroxybutyrate: Cytosolic and Mitochondrial Mechanisms
- 5. Evolution
- 5. Evolution
- Prebiotic Syntheses and the Mechanism of Early Chemical Evolution
- Prebiotic Roots of Informed Protein Synthesis: Nature of the Lipmann Connection
- A Case for an Additional RNA Base Pair in Early Evolution
- Inorganic Pyrophosphate in Cellular Energetics and Evolution
- Selforganization in Biosystems
- List of Contributors
- Acknowledgements
- Lipmann's Coworkers at Massachusetts General Hospital, Boston, and the Rockefeller University, New York
- Fritz Lipmann: Bibliography 1924-1985
- Index
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