Protein-Ligand Interactions : : Proceedings of the Symposium held at the University of Konstanz, Germany, September 1974 / / hrsg. von Gideon Blauer, Horst Sund.

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Bibliographic Details
Superior document:Title is part of eBook package: De Gruyter DGBA Medicine and Life Sciences - <1990
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HerausgeberIn:
Place / Publishing House:Berlin ;, Boston : : De Gruyter, , [2019]
©1975
Year of Publication:2019
Edition:Reprint 2019
Language:German
Online Access:
Physical Description:1 online resource (486 p.) :; Num. figs.
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Description
Other title:Frontmatter --
Preface --
Section I. General --
Letter from J. Wyman to the Members of the Symposium --
Concerted Changes in an Allosteric Macromolecule --
Ligand Interactions in Globular Proteins --
Discussion --
Ligand Binding to Enzyme Complexes --
Properties of Polymeric Proteins Bound to Solid Matrices: Subunit Exchange Chromatography --
Contributions of Aromatic Amino Acid Residues to the Optical Activity of Protein-Ligand Complexes --
Section II. Enzymes --
The Architecture of the Coenzyme Binding Domain in Dehydrogenases as Revealed by X-Ray Structure Analysis --
The Interaction of Glutamate Dehydrogenase with a Coenzyme Analog --
The Interaction of Adenosine Triphosphate and its Analogs with Myosin and the Modification by Actin --
Isolation of a Guanylnucleotide Binding Protein from Pigeon Erythrocyte Membranes --
On the Binding of Isoleucine and Related Amino Acids to Isoleucyl-tRNA Synthetase from Escherichia Coli MRE 600 --
The Effect of Small Molecules on the Affinity of Individual Chains in Hemoglobin and on its Cooperativity --
Cooperative Interactions without Symmetry or Subunits --
A Nuclear Magnetic Resonance Study of Activator Binding by Carboxypeptidase A --
Section III. Repressors --
Lactose Operator Sequences and the Action of Lac Repressor --
The Active Sites of Lac Repressor --
Lac Repressor --
The Use of Suppressed Nonsense Mutations to Generate Altered Lac Repressor Molecules --
Effect of Alterations in Lac Operator DNA on Repressor Binding --
Interaction of Lac Repressor with Non-Specific DNA Binding Sites --
Section IV. Receptors --
Binding and Functional States of the Cholinergic Receptor Protein from Torpedo Marmorata --
Subunit Structure and Binding Sites of the Acetylcholine Receptor --
Further Characterization of Purified Acetylcholine Receptor and its Incorporation into Phospholipid Vesicles --
Structural and Functional Studies of an Acetylcholine Receptor --
Section V. Antibodies, Drugs and Metabolites --
Antibody Combining Sites as a Model for Molecular Recognition --
Antibiotic Action on Enzymes Involved in Peptidoglycan Synthesis --
Problems in Studying Protein Binding with Regard to the Interaction of Steroids with a Specific Binding Globulin --
The Interaction of Low-Molecular Compounds with Serum Albumin as Measured by Optical Methods. Circular Dichroism of Bilirubin-Human Serum Albumin Complexes in the Presence of Alcohols in Aqueous Solution --
Section VI. Detergents and Electrolytes --
The Nature of Specific and Non-Specific Interactions of Detergents with Proteins: Complexing and Unfolding --
Interaction of Detergents with Proteins: Effect of Counter Ions on the System Ferrimyoglobin- Laurylpyridinium Halides in Aqueous Medium --
Influence of Ions on the Kinetics of Cooperative Conformational Changes in Globular Proteins --
Neutral Salt Effects on the Conformational Stability of Biological Macromolecules --
Concluding Remarks --
Index of Contributors --
Subject Index --
Backmatter
Format:Mode of access: Internet via World Wide Web.
ISBN:9783110830811
9783110637861
DOI:10.1515/9783110830811
Access:restricted access
Hierarchical level:Monograph
Statement of Responsibility: hrsg. von Gideon Blauer, Horst Sund.