Solubility in Pharmaceutical Chemistry /

Solubility in Pharmaceutical Chemistry / / ed. by Christoph Saal, Anita Nair.

This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify...

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Superior document:Title is part of eBook package: De Gruyter DG Ebook Package English 2020
MitwirkendeR:
Bauer-Brandl, Annette,
Beckmann, Wolfgang,
Berghausen, Joerg,
Brandl, Martin,
Desrayaud, Sandrine,
Dodd, Stephanie,
Dressman, Jennifer,
Elder, David,
Faller, Bernard,
Holm, René,
Laisney, Marc,
McDonagh, James L.,
Mitchell, John Bo,
Palmer, David S,
Reppas, Christos,
Saal, Christoph,
Skyner, Rachael E.,
Valko, Klara,
Vertzoni, Maria,
HerausgeberIn:
Nair, Anita,
Saal, Christoph,
Place / Publishing House:Berlin ;, Boston : : De Gruyter, , [2020]
©2020
Year of Publication:2020
Language:English
Online Access:
Physical Description:1 online resource (VIII, 362 p.)
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245 0 0 |a Solubility in Pharmaceutical Chemistry /  |c ed. by Christoph Saal, Anita Nair. 
264 1 |a Berlin ;  |a Boston :   |b De Gruyter,   |c [2020] 
264 4 |c ©2020 
300 |a 1 online resource (VIII, 362 p.) 
336 |a text  |b txt  |2 rdacontent 
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505 0 0 |t Frontmatter --   |t Contents --   |t List of contributors --   |t 1. Solubility – definition and basic physicochemical considerations --   |t 2. Solubility and supersaturation --   |t 3. In Silico methods to predict solubility --   |t 4. How solubility influences bioavailability --   |t 5. Estimation of intraluminal drug solubility --   |t 6. Biorelevant media --   |t 7. The role of solubility to optimize drug substances – a medicinal chemistry perspective --   |t 8. The role of solubility in optimizing drug products – a pharmaceutical development perspective --   |t 9. The relevance of solid-state forms for solubility --   |t 10. Solubility and phase behaviour from a drug substance manufacturing perspective --   |t 11. Biowaivers --   |t List of Abbreviations --   |t Index 
506 0 |a restricted access  |u http://purl.org/coar/access_right/c_16ec  |f online access with authorization  |2 star 
520 |a This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book. 
530 |a Issued also in print. 
538 |a Mode of access: Internet via World Wide Web. 
546 |a In English. 
588 0 |a Description based on online resource; title from PDF title page (publisher's Web site, viewed 27. Jan 2023) 
650 4 |a Arzneimittel. 
650 4 |a Formulierung. 
650 4 |a Löslichkeit. 
650 4 |a Wirkstofffreisetzung. 
650 7 |a MEDICAL / Pharmacology.  |2 bisacsh 
700 1 |a Bauer-Brandl, Annette,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Beckmann, Wolfgang,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Berghausen, Joerg,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Brandl, Martin,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Desrayaud, Sandrine,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Dodd, Stephanie,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Dressman, Jennifer,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Elder, David,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Faller, Bernard,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Holm, René,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Laisney, Marc,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a McDonagh, James L.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Mitchell, John Bo,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Nair, Anita,   |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Palmer, David S,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Reppas, Christos,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Saal, Christoph,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Saal, Christoph,   |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Skyner, Rachael E.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Valko, Klara,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Vertzoni, Maria,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
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