Animal Cell Biotechnology : : In Biologics Production / / ed. by Roland Wagner, Hansjörg Hauser.
This book introduces fundamental principles and practical application of techniques used in the scalable production of biopharmaceuticals with animal cell cultures. A broad spectrum of subjects relevant to biologics production and manufacturing are reviewed, including the generation of robust cell l...
Saved in:
Superior document: | Title is part of eBook package: De Gruyter DGBA Backlist Complete English Language 2000-2014 PART1 |
---|---|
MitwirkendeR: | |
HerausgeberIn: | |
Place / Publishing House: | Berlin ;, Boston : : De Gruyter, , [2014] ©2014 |
Year of Publication: | 2014 |
Language: | English |
Online Access: | |
Physical Description: | 1 online resource (702 p.) |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
LEADER | 13058nam a22016815i 4500 | ||
---|---|---|---|
001 | 9783110278965 | ||
003 | DE-B1597 | ||
005 | 20210830012106.0 | ||
006 | m|||||o||d|||||||| | ||
007 | cr || |||||||| | ||
008 | 210830t20142014gw fo d z eng d | ||
010 | |a 2014025725 | ||
019 | |a (OCoLC)979745314 | ||
020 | |a 9783110278965 | ||
024 | 7 | |a 10.1515/9783110278965 |2 doi | |
035 | |a (DE-B1597)175331 | ||
035 | |a (OCoLC)898422381 | ||
040 | |a DE-B1597 |b eng |c DE-B1597 |e rda | ||
041 | 0 | |a eng | |
044 | |a gw |c DE | ||
050 | 0 | 0 | |a TP248.27.A53 |b A5415 2015 |
072 | 7 | |a SCI049000 |2 bisacsh | |
082 | 0 | 4 | |a 660.6 |2 23 |
084 | |a WX 6600 |2 rvk |0 (DE-625)rvk/152214:13423 | ||
245 | 0 | 0 | |a Animal Cell Biotechnology : |b In Biologics Production / |c ed. by Roland Wagner, Hansjörg Hauser. |
264 | 1 | |a Berlin ; |a Boston : |b De Gruyter, |c [2014] | |
264 | 4 | |c ©2014 | |
300 | |a 1 online resource (702 p.) | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
347 | |a text file |b PDF |2 rda | ||
505 | 0 | 0 | |t Frontmatter -- |t Preface -- |t Contents -- |t List of Contributing Authors -- |t 1. Introduction -- |t 1.1 Industrial Use and Perspectives of Animal Cell Culture -- |t 2. Cell Lines -- |t 2.1 Generation of Cell Lines and Biotechnological Applications -- |t 2.2 CHO History, CHO Evolution and CHO Genomics – an Unsolvable Enigma? -- |t 2.3 Cell Lines for Vaccine Production -- |t 2.4 Cell Line Monitoring: Molecular Cytogenetic Characterization -- |t 2.5 Quality Control Essentials in Human Cell Culture: Cell Line Cross-contamination and Microbiological Infections -- |t 3. Genetic Engineering of Cells -- |t 3.1 Cell Line Evolution and Engineering -- |t 3.2 Chromosome Rearrangements and Gene Amplification -- |t 3.3 Synthetic Biology Principles for Engineering Mammalian Designer Cells -- |t 3.4 Rational Approaches for Transgene Expression: Targeted Integration and Episomal Maintenance -- |t 3.5 Manipulation of Cell Growth, Metabolism and Product Quality Attributes -- |t 4. Engineering of the Product -- |t 4.1 Control of Biotheraputics Glycosylation -- |t 4.2 Manufacturing of Complex Biotherapeutic Protein Products: Medical Need and Rational for Monoclonal Antibody Mixtures, Multispecific Formats, and Fc-fusion Proteins -- |t 5. Basic Aspects of Animal Cell Cultivation -- |t 5.1 Physiology and Metabolism of Animal Cells for Production -- |t 5.2 Functional -Omics for Cell Lines and Processes: The -Omics Technologies on the Example of CHO Cells -- |t 5.3 Nutrient Media for Cell Culture Technology -- |t 6. Upstream and Downstream Process Technology -- |t 6.1 Bioreactors for Animal Cell Culture -- |t 6.2 High Cell Density Cultivation Process -- |t 6.3 Industrial Cell Culture Process Scale-up Strategies and Considerations -- |t 6.4 Extraction and Purification of Biologics from Cell Culture: Monoclonal Antibody Downstream Processing -- |t 7. Monitoring and Control of Processes and Products -- |t 7.1 Concepts and Technologies for Advanced Process Monitoring and Control -- |t 7.2 Analytical Techniques and Quality Control of Protein Therapeutics -- |t 7.3 Process Characterization for Upstream and Downstream Process Development -- |t 8. Pharmaceutical Aspects of Biologics from Animal Cell Culture Processes -- |t 8.1 Spatiotemporally Controlled Delivery of Biopharmaceuticals -- |t Index |
506 | 0 | |a restricted access |u http://purl.org/coar/access_right/c_16ec |f online access with authorization |2 star | |
520 | |a This book introduces fundamental principles and practical application of techniques used in the scalable production of biopharmaceuticals with animal cell cultures. A broad spectrum of subjects relevant to biologics production and manufacturing are reviewed, including the generation of robust cell lines, a survey of functional genomics for a better understanding of cell lines and processes, as well as advances in regulatory compliant upstream and downstream development. The book is an essential reference for all those interested in translational animal cell-based pharmaceutical biotechnology. | ||
538 | |a Mode of access: Internet via World Wide Web. | ||
546 | |a In English. | ||
588 | 0 | |a Description based on online resource; title from PDF title page (publisher's Web site, viewed 30. Aug 2021) | |
650 | 0 | |a Animal cell biotechnology. | |
650 | 0 | |a Pharmaceutical biotechnology. | |
650 | 7 | |a SCIENCE / Life Sciences / Molecular Biology. |2 bisacsh | |
653 | |a Biologics Manufacturing. | ||
653 | |a Biopharmaceutical Engineering. | ||
653 | |a Biotechnology. | ||
653 | |a Cell Culture Engineering. | ||
653 | |a Virus Production. | ||
700 | 1 | |a Altamirano, Claudia, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Ausländer, David, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Baumann, Martina, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Bennun, Sandra V., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Berrios, Julio, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Betenbaugh, Michael J., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Blake, Emily, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Bollati-Fogolín, Mariela, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Borth, Nicole, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Brinkrolf, Karina, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Butler, Michael, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Ceaglio, Natalia, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Chung, Andrew, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Conley, Lynn, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Dirks, Wilhelm G., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Drexler, Hans G., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Eisenkraetzer, Detlef, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Etcheverrigaray, Marina, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Florin, Lore, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Fontes, Nuno, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Frandsen, Torben P., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Fussenegger, Martin, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Goesmann, Alexander, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Hackl, Matthias, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Hauser, Hansjörg, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Hauser, Hansjörg, |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
700 | 1 | |a Heffner, Kelley M., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Henning von Horsten, Hans, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Hoffrogge, Raimund, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Hong Que, Amy, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Hu, Weiwei, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Janakiraman, Vijay, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Jordan, Ingo, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Kaufmann, Hitto, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Kratje, Ricardo, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Kruse, Natascha, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Lee, Kyoungho, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Lipps, Christoph, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a MacLeod, Roderick A. F., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a May, Tobias, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Müller, Dethardt, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Noll, Thomas, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Oggero, Marcos, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Omasa, Takeshi, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Pühler, Alfred, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Rasmussen, Sören K., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Rebmann, Balder, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Ryll, Thomas, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Sandig, Volker, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Smelko, John Paul, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Spencer, Shawal, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Tauch, Andreas, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Tayi, Venkata, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Tolstrup, Anne B., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Uphoff, Cord C., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Vergara, Mauricio, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Vogel, Jens H., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Wagner, Roland, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Wagner, Roland, |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
700 | 1 | |a Wang, Yang, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Weber, Wilfried, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Westoby, Matthew, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Wiltberger, Kelly, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Winkler, Karsten, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Wirth, Dagmar, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Wurm, Florian M., |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Zhang, Ruoheng, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Ziyi Kan, Steven, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a Zurbriggen, Matias, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
700 | 1 | |a van Hoogevest, Peter, |e contributor. |4 ctb |4 https://id.loc.gov/vocabulary/relators/ctb | |
773 | 0 | 8 | |i Title is part of eBook package: |d De Gruyter |t DGBA Backlist Complete English Language 2000-2014 PART1 |z 9783110238570 |
773 | 0 | 8 | |i Title is part of eBook package: |d De Gruyter |t DGBA Backlist Medicine and Life Sciences 2000-2014 (EN) |z 9783110238495 |
773 | 0 | 8 | |i Title is part of eBook package: |d De Gruyter |t DGBA Medicine and Life Sciences 2000 - 2014 |z 9783110637915 |o ZDB-23-GML |
773 | 0 | 8 | |i Title is part of eBook package: |d De Gruyter |t EBOOK PACKAGE Chemistry, Materials Sc, Biol, Geosc 2014 |z 9783110369601 |o ZDB-23-DCM |
773 | 0 | 8 | |i Title is part of eBook package: |d De Gruyter |t EBOOK PACKAGE Complete Package 2014 |z 9783110369526 |o ZDB-23-DGG |
776 | 0 | |c EPUB |z 9783110381429 | |
776 | 0 | |c print |z 9783110278866 | |
856 | 4 | 0 | |u https://doi.org/10.1515/9783110278965 |
856 | 4 | 0 | |u https://www.degruyter.com/isbn/9783110278965 |
856 | 4 | 2 | |3 Cover |u https://www.degruyter.com/cover/covers/9783110278965.jpg |
912 | |a 978-3-11-023849-5 DGBA Backlist Medicine and Life Sciences 2000-2014 (EN) |c 2000 |d 2014 | ||
912 | |a 978-3-11-023857-0 DGBA Backlist Complete English Language 2000-2014 PART1 |c 2000 |d 2014 | ||
912 | |a EBA_BACKALL | ||
912 | |a EBA_DGALL | ||
912 | |a EBA_EBACKALL | ||
912 | |a EBA_EBKALL | ||
912 | |a EBA_EEBKALL | ||
912 | |a EBA_ESTMALL | ||
912 | |a EBA_STMALL | ||
912 | |a GBV-deGruyter-alles | ||
912 | |a PDA12STME | ||
912 | |a PDA13ENGE | ||
912 | |a PDA18STMEE | ||
912 | |a PDA5EBK | ||
912 | |a ZDB-23-DCM |b 2014 | ||
912 | |a ZDB-23-DGG |b 2014 | ||
912 | |a ZDB-23-GML |c 2000 |d 2014 |