Biopharmaceutics modeling and simulations : theory, practice, methods, and applications / / Kiyohiko Sugano.

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Year of Publication:2012
Language:English
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Physical Description:xxxv, 483 p. :; ill.
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020 |z 9781118188330 (cloth) 
020 |z 9781118028681 (cloth) 
020 |a 9781118354315 (electronic bk.) 
035 |a (MiAaPQ)500875932 
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050 4 |a RM301.4  |b .S84 2012 
082 0 4 |a 615.7  |2 23 
100 1 |a Sugano, Kiyohiko. 
245 1 0 |a Biopharmaceutics modeling and simulations  |h [electronic resource] :  |b theory, practice, methods, and applications /  |c Kiyohiko Sugano. 
260 |a Hoboken, N.J. :  |b Wiley,  |c c2012. 
300 |a xxxv, 483 p. :  |b ill. 
504 |a Includes bibliographical references and index. 
505 0 |a Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice. 
533 |a Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. 
650 0 |a Biopharmaceutics  |x Simulation methods. 
650 0 |a Computer simulation. 
655 4 |a Electronic books. 
710 2 |a ProQuest (Firm) 
856 4 0 |u https://ebookcentral.proquest.com/lib/oeawat/detail.action?docID=875932  |z Click to View