Biopharmaceutics modeling and simulations : theory, practice, methods, and applications / / Kiyohiko Sugano.
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Year of Publication: | 2012 |
Language: | English |
Online Access: | |
Physical Description: | xxxv, 483 p. :; ill. |
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008 | 120224s2012 njua sb 001 0 eng d | ||
010 | |z 2012007296 | ||
020 | |z 9781118188330 (cloth) | ||
020 | |z 9781118028681 (cloth) | ||
020 | |a 9781118354315 (electronic bk.) | ||
035 | |a (MiAaPQ)500875932 | ||
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040 | |a MiAaPQ |c MiAaPQ |d MiAaPQ | ||
050 | 4 | |a RM301.4 |b .S84 2012 | |
082 | 0 | 4 | |a 615.7 |2 23 |
100 | 1 | |a Sugano, Kiyohiko. | |
245 | 1 | 0 | |a Biopharmaceutics modeling and simulations |h [electronic resource] : |b theory, practice, methods, and applications / |c Kiyohiko Sugano. |
260 | |a Hoboken, N.J. : |b Wiley, |c c2012. | ||
300 | |a xxxv, 483 p. : |b ill. | ||
504 | |a Includes bibliographical references and index. | ||
505 | 0 | |a Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice. | |
533 | |a Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. | ||
650 | 0 | |a Biopharmaceutics |x Simulation methods. | |
650 | 0 | |a Computer simulation. | |
655 | 4 | |a Electronic books. | |
710 | 2 | |a ProQuest (Firm) | |
856 | 4 | 0 | |u https://ebookcentral.proquest.com/lib/oeawat/detail.action?docID=875932 |z Click to View |