Inflammation in Cancellous and Cortical Bone Healing.
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Superior document: | Linköping University Medical Dissertations Series ; v.1668 |
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Place / Publishing House: | Linköping : : Linkopings Universitet,, 2019. {copy}2019. |
Year of Publication: | 2019 |
Edition: | 1st ed. |
Language: | English |
Series: | Linköping University Medical Dissertations Series
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Online Access: | |
Physical Description: | 1 online resource (80 pages) |
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Table of Contents:
- Intro
- POPULÄRVETENSKAPLIG SAMMANFATTNING
- ABSTRACT
- Acknowledgments
- Contents
- List of Figures
- List of Tables
- List of Terms
- List of Cell Types
- List of Phenotypic Markers
- Thesis at a Glance
- List of Papers
- Relevant Work Not Included in This Thesis
- Nomenclature
- Anatomy vs. Physiology
- Introduction
- Previous Work
- Background and Rationale
- Research Aims
- Inflammation in Bone Healing
- Blood Counts Differ Between Humans and Mice
- Myeloid Cells
- Granulocytes Might Be Important Initiators of Fracture Healing
- Monocytes Show a Continuum of Functionality
- M1 and M2 Macrophages in Bone Healing
- Macrophages Appear Vital To Osteoblasts
- Lymphoid Cells
- Lymphocytes Are Indeed Present at the Fracture Site
- Subsets of Lymphocytes Might Have Specific Roles in Bone Healing
- The Role of B Cells in Fracture Healing Is Unknown
- Anti-inflammatory Agents
- Nerves Supply Trophic Signals To Bone
- Comments on Material and Methods
- Models of Fracture Healing
- Do Mice Faithfully Model Human Bone Healing?
- Fracture Models in Mice Are Synonymous with Shaft Fracture
- Cancellous Model
- Cortical Model
- Bone Healing Model vs. Fracture Model
- Flow Cytometry
- Finding Cells in Bone
- Finding Cells in the Flow Cytometer
- Where Does a Cloud Really End?
- Some Phenotypes Are Bright and Some Dull
- Mass Spectrometry
- The power of a p value
- Results and Discussion
- Inflammatory Response on Metaphsyeal Trauma
- Mirrored Inflammation
- The Systemic Response Is Not Neurally Mediated
- Cells Specific To Cancellous Bone Healing
- M1 and M2
- Lymphocytes
- Macrophages Are Essential
- Different Cell Recruitment
- Different Response
- Inflammations is Increased at Day 3
- The Role of B Cells in Fracture Healing Is Unknown
- Concluding Remarks and Future
- Bibliography
- Papers.