Inflammation in Cancellous and Cortical Bone Healing.

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Bibliographic Details
Superior document:Linköping University Medical Dissertations Series ; v.1668
:
Place / Publishing House:Linköping : : Linkopings Universitet,, 2019.
{copy}2019.
Year of Publication:2019
Edition:1st ed.
Language:English
Series:Linköping University Medical Dissertations Series
Online Access:
Physical Description:1 online resource (80 pages)
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Table of Contents:
  • Intro
  • POPULÄRVETENSKAPLIG SAMMANFATTNING
  • ABSTRACT
  • Acknowledgments
  • Contents
  • List of Figures
  • List of Tables
  • List of Terms
  • List of Cell Types
  • List of Phenotypic Markers
  • Thesis at a Glance
  • List of Papers
  • Relevant Work Not Included in This Thesis
  • Nomenclature
  • Anatomy vs. Physiology
  • Introduction
  • Previous Work
  • Background and Rationale
  • Research Aims
  • Inflammation in Bone Healing
  • Blood Counts Differ Between Humans and Mice
  • Myeloid Cells
  • Granulocytes Might Be Important Initiators of Fracture Healing
  • Monocytes Show a Continuum of Functionality
  • M1 and M2 Macrophages in Bone Healing
  • Macrophages Appear Vital To Osteoblasts
  • Lymphoid Cells
  • Lymphocytes Are Indeed Present at the Fracture Site
  • Subsets of Lymphocytes Might Have Specific Roles in Bone Healing
  • The Role of B Cells in Fracture Healing Is Unknown
  • Anti-inflammatory Agents
  • Nerves Supply Trophic Signals To Bone
  • Comments on Material and Methods
  • Models of Fracture Healing
  • Do Mice Faithfully Model Human Bone Healing?
  • Fracture Models in Mice Are Synonymous with Shaft Fracture
  • Cancellous Model
  • Cortical Model
  • Bone Healing Model vs. Fracture Model
  • Flow Cytometry
  • Finding Cells in Bone
  • Finding Cells in the Flow Cytometer
  • Where Does a Cloud Really End?
  • Some Phenotypes Are Bright and Some Dull
  • Mass Spectrometry
  • The power of a p value
  • Results and Discussion
  • Inflammatory Response on Metaphsyeal Trauma
  • Mirrored Inflammation
  • The Systemic Response Is Not Neurally Mediated
  • Cells Specific To Cancellous Bone Healing
  • M1 and M2
  • Lymphocytes
  • Macrophages Are Essential
  • Different Cell Recruitment
  • Different Response
  • Inflammations is Increased at Day 3
  • The Role of B Cells in Fracture Healing Is Unknown
  • Concluding Remarks and Future
  • Bibliography
  • Papers.