Micro-, Meso- and Macro-Connectomics of the Brain.

Micro-, Meso- and Macro-Connectomics of the Brain.

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Bibliographic Details
Superior document:Research and Perspectives in Neurosciences Series
:
Kennedy, Henry.
TeilnehmendeR:
Van Essen, David C.
Christen, Yves.
Place / Publishing House:Cham : : Springer International Publishing AG,, 2016.
Ã2016.
Year of Publication:2016
Edition:1st ed.
Language:English
Series:Research and Perspectives in Neurosciences Series
Online Access:
Physical Description:1 online resource (173 pages)
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Table of Contents:
  • Intro
  • Acknowledgments
  • Contents
  • List of Contributors
  • Nanoconnectomics
  • Nanoconnectomics
  • Extracellular Space
  • Simulating Signaling in Small Spaces
  • Precision of Synaptic Plasticity
  • References
  • Inhibitory Cell Types, Circuits and Receptive Fields in Mouse Visual Cortex
  • Differences in Connectivity, Visual Responses and Functional Impact of PV Versus SST Interneurons
  • Calretinin (CR) and VIP-Expressing Interneurons Target SST Interneurons
  • Functional Impact of VIP Interneurons
  • References
  • Form Meets Function in the Brain: Observing the Activity and Structure of Specific Neural Connections
  • Introduction
  • CLARITY
  • Clarifying Large Tissue Volumes
  • CLARITY-Optimized Light Sheet Microscopy
  • Tracking Activity in Deep Genetically Targeted Neurons of Behaving Animals
  • Neural Activity that Encodes and Predicts Social Interaction
  • Outlook
  • References
  • The Network for Intracortical Communication in Mouse Visual Cortex
  • Introduction
  • Thalamocortical Projections to Mouse Visual Cortex
  • Cortical Cartography
  • Areal Organization of Visual Cortex
  • Interareal Connections
  • Cortical Hierarchy
  • Synaptic Organization of Feedforward and Feedback Connections
  • Dorsal and Ventral Processing Streams
  • References
  • The Brain in Space
  • Introduction
  • The Promise of Network Theory
  • Empirical Evidence for a Principled Model of Cortical Connectivity: The EDR Model
  • The Cortical Core-Periphery Structure
  • Biology, Clustering and the Importance of Weak Links
  • Conclusion and Perspectives
  • References
  • In-Vivo Connectivity in Monkeys
  • Anatomical, Functional and Effective Connectivity in Animal Models
  • Towards Causality: Effective Connectivity with Focal Perturbation Tools
  • Effective Connectivity: Combined Electrical Microstimulation and Whole-Brain fMRI.
  • Novel Genetically-Based Perturbation Methods?
  • References
  • Parcellations and Connectivity Patterns in Human and Macaque Cerebral Cortex
  • Introduction
  • Cortical Cartography and Parcellation
  • Distributed Cortical Connectivity
  • Interspecies Registration
  • Concluding Comments
  • References
  • Connectome Networks: From Cells to Systems
  • Defining the Connectome
  • Brain Networks and Graph Theory
  • Topology of Structural Brain Networks
  • Microscale
  • Mesoscale
  • Macroscale
  • Comparison Across Scales and Challenges
  • Relations Between Structure and Function
  • Microscale
  • Mesoscale
  • Macroscale
  • Comparison Across Scales and Challenges
  • Future Perspectives
  • References
  • Intra- and Inter-hemispheric Connectivity Supporting Hemispheric Specialization
  • Introduction
  • Human Dualism: Two Hands, Two Brains
  • Asymmetries Measured with Brain Imaging
  • Anatomo-Functional Support of HS
  • Gray Matter Macroscopic Asymmetries and HS
  • White Matter Connections Supporting HS
  • Corpus Callosum
  • Intra-hemispheric Structural Connectivity
  • Functional Asymmetries and Hemispheric Dominance for Language Assessed with Meta-analysis
  • Developmental Course of the Setting Up of Anatomical and Functional Asymmetries
  • HS, Cognitive Abilities and Developmental/Psychiatric Diseases
  • Cognitive Skills and Asymmetries
  • Language HS, Developmental and Psychiatric Diseases
  • Inter-individual Variability in HS: Factors at Play
  • BILandGIN: A Multimodal Database for Investigating HS
  • Conclusion
  • References
  • Genetics of the Connectome and the ENIGMA Project
  • Background to ENIGMA
  • Genetic Influences on the Brain
  • Finding the Genes Involved
  • GWAS of the Brain
  • Counterarguments and Power
  • Non-biological Information Arising from ENIGMA
  • But Do the ENIGMA Genes Affect Disease Risk?
  • Searching Brain Images for Statistical Effects.
  • Brain-Wide Genome-Wide Scanning
  • Genetic Screening of the Connectome
  • Caveats for Multi-site Genomic Analysis of the Connectome
  • Future Directions: Adaptive Connectomics and EPIC
  • References
  • Index.

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