Stem Cells in Neuroendocrinology.
Saved in:
Superior document: | Research and Perspectives in Endocrine Interactions Series |
---|---|
: | |
TeilnehmendeR: | |
Place / Publishing House: | Cham : : Springer International Publishing AG,, 2016. ©2016. |
Year of Publication: | 2016 |
Edition: | 1st ed. |
Language: | English |
Series: | Research and Perspectives in Endocrine Interactions Series
|
Online Access: | |
Physical Description: | 1 online resource (163 pages) |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
LEADER | 06946nam a22004333i 4500 | ||
---|---|---|---|
001 | 5005579785 | ||
003 | MiAaPQ | ||
005 | 20240229073831.0 | ||
006 | m o d | | ||
007 | cr cnu|||||||| | ||
008 | 240229s2016 xx o ||||0 eng d | ||
020 | |a 9783319416038 |q (electronic bk.) | ||
020 | |z 9783319416021 | ||
035 | |a (MiAaPQ)5005579785 | ||
035 | |a (Au-PeEL)EBL5579785 | ||
035 | |a (OCoLC)955309603 | ||
040 | |a MiAaPQ |b eng |e rda |e pn |c MiAaPQ |d MiAaPQ | ||
050 | 4 | |a RC321-580 | |
100 | 1 | |a Pfaff, Donald. | |
245 | 1 | 0 | |a Stem Cells in Neuroendocrinology. |
250 | |a 1st ed. | ||
264 | 1 | |a Cham : |b Springer International Publishing AG, |c 2016. | |
264 | 4 | |c ©2016. | |
300 | |a 1 online resource (163 pages) | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
490 | 1 | |a Research and Perspectives in Endocrine Interactions Series | |
505 | 0 | |a Intro -- Introduction -- Acknowledgments -- Contents -- List of Contributors -- A Brief Overview of Techniques for Modulating Neuroendocrine and Other Neural Systems -- A Brief View of the Oldest, Most Primitive Approaches -- The Disciplines -- Morphology -- Physiology -- Chemistry -- Genetics, Genomics -- Cognitive Neuroscience -- Computational Approaches -- A Brief Survey of Emerging Techniques for Neuromodulation -- Electrical -- Chemical -- Genetic -- Viral -- Computational -- Special Opportunities for Manipulating the Unique Products of Neuroendocrine Neurons -- This Volume -- Further Reading -- Basics of Stem Cell Biology as Applied to the Brain -- Introduction -- The Basic Biology of Stem Cells -- Preimplantation Development and Embryonic Stem (ES) Cells -- Derivation and Maintenance of Pluripotent Stem Cells: Differences Between Mouse and Human -- How to Test Pluripotency? -- Opportunities and Challenges for Using ES Cells in Medicine -- Obtaining Cells Genetically Matched to Patients: Reprogramming, Cloning, and Induced Pluripotent Stem Cells -- Opportunities and Challenges of Producing Hypothalamic Neurons from Stem Cells -- Direct Reprogramming: An Alternative Pathway to Obtaining Patient-Matched Neuron-Like Cells -- Relevance of In Vitro Cell Types to Neuronal Biology -- Outlook -- References -- Human Pluripotent-Derived Lineages for Repairing Hypopituitarism -- Derivation of Human Neural Cell Types for Regenerative Medicine -- Derivation and Application of Human Pituitary Lineages -- Perspectives and Challenges on the Road to Translation -- Conclusion -- References -- Recapitulating Hypothalamus and Pituitary Development Using Embryonic Stem/Induced Pluripotent Stem Cells -- Introduction -- A Need for Hypothalamus and Adenohypophysis Regenerative Medicine -- Mouse ES Cells -- Pituitary Gland Embryology. | |
505 | 8 | |a Three-Dimensional ES Cell Culture -- Induction of Hypothalamic Neurons from Mouse ES Cells -- Two-Layer Formation In Vitro Is the First Step of Adenohypohysis Differentiation -- Self-Formation of Rathkeś Pouch -- Differentiation Into Hormone-Producing Endocrine Cells -- Functionality of Induced ACTH+ Cells -- Effect of Transplantation Into Hypophysectomized Model Animals -- Adaptation to Human ES/iPS Cell Culture -- Future Perspectives -- References -- Regulation of Body Weight and Metabolism by Tanycyte-Derived Neurogenesis in Young Adult Mice -- Introduction -- Material and Methods -- Animals -- Caloric Restriction -- Reagents -- Bromodeoxyuridine (BrdU) -- Tissue Processing and Antibodies -- Immunohistochemistry -- Cell Quantification -- Focal Irradiation of Ventrobasal Hypothalamus -- Longitudinal Collection of Weight Data -- Statistical Analysis -- Results -- Dietary Signals Differentially Regulate Neurogenesis and Cell Proliferation in ME and ArcN -- Sex-Specific Differences in Diet-Induced Hypothalamic Neurogenesis -- Blocking Neurogenesis in ME Attenuates HFD-Induced Weight Gain in Young Adult Female, But Not Male, Mice -- Discussion -- References -- Genetic Dissection of the Neuroendocrine and Behavioral Responses to Stressful Challenges -- References -- Pituitary Stem Cells: Quest for Hidden Functions -- Introduction -- Primer on Pituitary Biology and Pathology -- Pituitary Stem Cells: Expanding Molecular Portrayal -- Pituitary Stem Cells: Uncovering the Hidden Functions -- Neonatal Pituitary Maturation -- Basal and Adapting Adult Pituitary -- Pituitary Regeneration and Impact of Aging -- Pituitary Tumorigenesis -- Conclusion and General Perspectives -- References -- Pituitary Stem Cells During Normal Physiology and Disease -- Introduction -- The Long-Term Maintenance of the Anterior Pituitary -- Stem Cells and Pituitary Tumours. | |
505 | 8 | |a References -- Epigenetic Mechanisms of Pituitary Cell Fate Specification -- Introduction -- Escaping Stemness -- Intermediate Pituitary Identity -- Pax7 Opens a New Enhancer Repertoire -- The Essence of Pioneering -- Succeeding at Multiple Choices or Avoiding Cellular Schizophrenia -- Future Challenges -- References -- Advances in Stem Cells Biology: New Approaches to Understand Depression -- Introduction -- How Can We Best Study Depression? -- The Neurogenesis Theory of Depression -- Experimental Approaches -- Immortalized Human Neural Cell Lines -- Neural Stem Cell Lines -- Modeling the Role of Stress -- Modeling the Role of Inflammation and Oxidative Stress -- Studying Mechanism of Action of Antidepressants -- Tumour-Derived Cell Lines -- Patient-Derived Neural Cells -- IPSCs -- Olfactory Neuroepithelium-Derived Stem Cells -- Conclusions and Limitations of the Cell Models -- References -- Perspective on Stem Cells in Developmental Biology, with Special Reference to Neuroendocrine Systems -- Introduction -- Morphogenesis of the Hypothalamo-Pituitary Axis (Fig.1) -- Hypothalamus -- Pituitary -- Characterization of AdSC in the Hypothalamo-Pituitary Axis (Fig.3) -- Hypothalamus -- Pituitary -- In vitro Recapitulation of Ontogenesis in the Hypothalamo-Pituitary Axis (Fig.3) -- Induction of Hypothalamic Identity from 3D ESC Aggregates -- Generation of Hypothalamic Neurons from 2D ESC Cultures -- Induction of RP from 3D Aggregates -- Perspectives -- Differentiation Strategies -- Implantation in Homotypic Locations -- Conclusion -- References. | |
588 | |a Description based on publisher supplied metadata and other sources. | ||
590 | |a Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. | ||
655 | 4 | |a Electronic books. | |
700 | 1 | |a Christen, Yves. | |
776 | 0 | 8 | |i Print version: |a Pfaff, Donald |t Stem Cells in Neuroendocrinology |d Cham : Springer International Publishing AG,c2016 |z 9783319416021 |
797 | 2 | |a ProQuest (Firm) | |
830 | 0 | |a Research and Perspectives in Endocrine Interactions Series | |
856 | 4 | 0 | |u https://ebookcentral.proquest.com/lib/oeawat/detail.action?docID=5579785 |z Click to View |