On Protein Structure, Function and Modularity from an Evolutionary Perspective.
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| Superior document: | Linköping Studies in Science and Technology. Dissertations Series ; v.1914 |
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| Place / Publishing House: | Linköping : : Linkopings Universitet,, 2018. {copy}2018. |
| Year of Publication: | 2018 |
| Edition: | 1st ed. |
| Language: | English |
| Series: | Linköping Studies in Science and Technology. Dissertations Series
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| Online Access: | |
| Physical Description: | 1 online resource (204 pages) |
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Table of Contents:
- Intro
- Abstract
- Acknowledgments
- Author Contributions
- Contents
- List of Figures
- Abbreviations
- Introduction
- What is Science?
- Life and its Molecules
- Proteins - order and disorder
- Systems
- Thesis
- Method
- Alignments
- Contact prediction
- Structure prediction
- Dynamics simulation
- Clustering analysis
- Essential Dynamics Analysis
- Graphs and Structures
- Allosteric Network Analysis
- Ensemble Quality Assessment
- Present Investigations
- Function in transiently ordered islets of intrinsically disordered proteins (Paper I)
- Functional analysis of protein structure dynamics using graph models and multivariate statistics (Paper II)
- Improvements in Protein Model Quality Assessment from Automated Domain Partitioning using Spectral Clustering (Paper III and Manuscript I)
- Functional Interaction Network of c-MYC Conserved Regions determined by Evolutionary Couplings (Manuscript II)
- Conclusion
- Future Perspectives
- Bibliography
- Paper I
- Paper II
- Paper III
- Manuscript I
- Manuscript II.