Integrated cardiac safety : assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance /

Integrated cardiac safety : assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance / / J. Rick Turner, Todd A. Durham.

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ProQuest (Firm)
Turner, J. Rick.
TeilnehmendeR:
Durham, Todd A.
ProQuest (Firm)
Year of Publication:2009
Language:English
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Physical Description:xxviii, 470 p. :; ill.
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100 1 |a Turner, J. Rick. 
245 1 0 |a Integrated cardiac safety  |h [electronic resource] :  |b assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance /  |c J. Rick Turner, Todd A. Durham. 
260 |a Hoboken, N.J. :  |b John Wiley & Sons,  |c c2009. 
300 |a xxviii, 470 p. :  |b ill. 
504 |a Includes bibliographical references (p. 397-455) and index. 
505 0 |a The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety. 
533 |a Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. 
650 0 |a Cardiovascular toxicology. 
650 0 |a Heart  |x Effect of drugs on. 
650 0 |a Drugs  |x Side effects  |x Testing. 
650 0 |a Drugs  |x Safety measures. 
655 4 |a Electronic books. 
700 1 |a Durham, Todd A. 
710 2 |a ProQuest (Firm) 
856 4 0 |u https://ebookcentral.proquest.com/lib/oeawat/detail.action?docID=406462  |z Click to View 

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