Robustness and evolvability in living systems / / Andreas Wagner.
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| Place / Publishing House: | Princeton, New Jersey : : Princeton University Press,, [2005] 2005 |
| Year of Publication: | 2005 |
| Language: | English |
| Series: | Princeton studies in complexity
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| Online Access: | |
| Physical Description: | 1 online resource (384 pages) :; illustrations. |
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Table of Contents:
- Introduction
- The genetic alphabet
- The genetic code
- RNA structure
- Proteins and point mutations
- Proteins and recombination
- Regulatory DNA regions and their reorganization in evolution
- Metabolic pathways
- Metabolic networks
- Drosophila segmentation and other gene regulatory networks
- Phenotypic traits, cryptic variation, and human diseases
- The many ways of building the same body
- Neutral spaces
- Evolvability and neutral mutations
- Redundancy of parts or distributed robustness?
- Robustness as an evolved adaptation to mutations
- Robustness as an evolved adapatation to environmental change and noise
- Robustness and fragility: advantages to variation and trade-offs
- Robustness in natural systems and self-organization
- Robustness in man-made systems.