Robustness and evolvability in living systems / / Andreas Wagner.

• Author: Wagner, Andreas, 1967 January 26-
• Place / Publishing House: Princeton, New Jersey : : Princeton University Press,, [2005]; 2005
• Year of Publication: 2005
• Language: English
• Series: Princeton studies in complexity
• Physical Description: 1 online resource (384 pages) :; illustrations.

Table of Contents

Introduction -- The genetic alphabet -- The genetic code -- RNA structure -- Proteins and point mutations -- Proteins and recombination -- Regulatory DNA regions and their reorganization in evolution -- Metabolic pathways -- Metabolic networks -- Drosophila segmentation and other gene regulatory networks -- Phenotypic traits, cryptic variation, and human diseases -- The many ways of building the same body -- Neutral spaces -- Evolvability and neutral mutations -- Redundancy of parts or distributed robustness? -- Robustness as an evolved adaptation to mutations -- Robustness as an evolved adapatation to environmental change and noise -- Robustness and fragility: advantages to variation and trade-offs -- Robustness in natural systems and self-organization -- Robustness in man-made systems.