Using animal models in biomedical research : a primer for the investigator / / Pierce K.H. Chow, Robert T.H. Ng, Bryan E. Ogden.
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| Year of Publication: | 2008 |
| Language: | English |
| Online Access: | |
| Physical Description: | xviii, 290 p. :; ill. (some col.). |
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| 082 | 0 | 4 | |a 610.284 |2 22 |
| 100 | 1 | |a Chow, Pierce K. H. | |
| 245 | 1 | 0 | |a Using animal models in biomedical research |h [electronic resource] : |b a primer for the investigator / |c Pierce K.H. Chow, Robert T.H. Ng, Bryan E. Ogden. |
| 260 | |a Hackensack, NJ : |b World Scientific, |c c2008. | ||
| 300 | |a xviii, 290 p. : |b ill. (some col.). | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a 1. Scientific considerations and choice of species. The rationale for the use of animal models in biomedical research / Pierce Chow. Experimental animal models in biomedical resarch / Robert Ng. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- 2. Regulatory considerations in the use of animal models. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. The functions of the institutional animal care and use committee / Pierce Chow. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. The 3r's, research variables and the use of alternatives / Hock Soo Ong. Use of statistics as determinant for number of animals used / Huihua Li. The advantages of accreditation with AAALAC / Bryan Ogden -- 3. Animal handling and surgical procedures. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. Blood collection from laboratory animals / Jason Villano. Antibiotic coverage and therapy / Darvi Sergio. Animal preparation and transport / Robert Ng. Preparation and implementation of animal surgery / Robert Ng. Animal intubation / Robert Ng. Anaesthesia and maintenance of homeostasis / Robert Ng. animal euthanasia / Darvi Sergio. Rodent sentinel programme / Peik Khin Tan -- | |
| 505 | 0 | |a 4. Basic animal investigative methods. Bioimaging in animals / David Ng ... [et al.]. Histology sampling and techniques / In Chin Song. Animal tissue perfusion and preservation / Robert Ng. Animal cell culture / Peggy Yong and Kai Zhang. Application of microsurgical techniques in animal research / Bien Keem Tan ... [et al.] -- 5. Animal welfare considerations. Species specific caging configuration and design / Cindy Phua. Postoperative care and pain management / Jason Villano. animal feeds and nutritional requirements / Peik Khin Tan -- 6. Safety management of an animal facility. Occupational health and safety programme / Angela Goh. New employee and external users orientation / Inria Kurniawan Then. Radiation safety awareness in animal research / S. Somanesan. Emergency crisis management / Irene Kee. Zoonoses and laboratory animal allergies / Jason Villano -- 7. Supporting facilities design. clinical skills laboratory / Robert Ng. Animal research supporting laboratories / Robert Ng. animal research and housing facilities / Robert Ng -- 8. The development of comprehensive animal facilities in Singapore. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng -- Append. 1. Accredited laboratories for import of experimental animals -- Append. 2. Radiation safety data -- Append. 3. Anaesthesia for laboratory animals -- Append. 4. Analgesics and therapeutics for laboratory animals -- Append. 5. Passively transmitted zoonotic organisms. | |
| 533 | |a Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. | ||
| 650 | 0 | |a Animal models in research. | |
| 650 | 0 | |a Medicine |x Research. | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Ng, Robert T. H. | |
| 700 | 1 | |a Ogden, Bryan E. | |
| 710 | 2 | |a ProQuest (Firm) | |
| 856 | 4 | 0 | |u https://ebookcentral.proquest.com/lib/oeawat/detail.action?docID=1193374 |z Click to View |