The cost manual of laboratory animal care and use : : refinement, reduction, and research / / edited by Bryan Howard, Timo Nevalainen and Gemma Perretta.

Judge Your Practices Against This Benchmark Manual COST Action B-24 established four working groups to research and discuss issues relevant to laboratory animal science. These included the housing of animals, environmental needs, refinement of procedures, genetically modified animals, and cost-benef...

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Place / Publishing House:Boca Raton, FL : : CRC Press, an imprint of Taylor and Francis,, 2010.
Year of Publication:2010
Edition:First edition.
Language:English
Physical Description:1 online resource (424 pages)
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Table of Contents:
  • chapter 1 Introduction
  • chapter 2 Design and Oversight of Laboratory Animal Facilities
  • chapter 3 Housing and Care of Laboratory Animals
  • chapter 4 Animal Needs and Environmental Refinement
  • chapter 5 Ethical Evaluation of ScientificProcedures: Recommendations for Ethics Committees
  • chapter 6 Reduction by Careful Design and Statistical Analysis
  • chapter 7 Animal Models: Selecting and Preparing Animals for a Study
  • chapter 8 Creation of Genetically Modified Animals
  • chapter 9 Management of Genetically Modified Rodents
  • chapter 10 Impact of Handling,Radiotelemetry, and Food Restriction
  • chapter 11 Basic Procedures: Dosing,Sampling and Immunisation
  • chapter 12 Imaging Techniques
  • chapter 13 Anaesthesia and Analgesia
  • chapter 14 Use of Humane Endpointsto Minimise Suffering
  • chapter 15 Euthanasia
  • chapter 16 Education, Training,and Competence
  • chapter 17 Animal Experimentation and Open Communication.