Persistent Organic Pollutants in Human Milk / edited by Rainer Malisch, Peter Fürst, Kateřina Šebková.

• HerausgeberIn: Malisch, Rainer.; Fürst, Peter.; Šebková, Kateřina.
• Place / Publishing House: Cham : : Springer International Publishing :, Imprint: Springer,, 2023.
• Year of Publication: 2023
• Edition: 1st ed. 2023.
• Language: English
• Physical Description: 1 online resource (XXVII, 683 p. 318 illus., 309 illus. in color.)

This open access book reviews the trends of persistent organic pollutants (POPs) in human milk and discusses the main findings of five global surveys that were coordinated by the World Health Organization (WHO) and the United Nations Environment Programme (UNEP) from 2000 to 2019. Human milk was selected as core matrix for human exposure under the Global Monitoring Plan for effectiveness evaluation of the Stockholm Convention on Persistent Organic Pollutants. Milk from well-defined groups of mothers was collected and mixed to form a representative sample per country. Datasets collected represent the largest global human tissues survey with a harmonized protocol, carried out in a uniform format for more than two decades. Altogether 69 countries participated in these studies between 2000 and 2015, and more than 40 countries participated in the study from 2016 to 2019. Divided into 5 parts, the book offers an authoritative overview of human milk biomonitoring; collates the harmonized sampling requirements and analytical methods for the identification and quantification of contaminants in human milk; examines the results of the WHO/UNEP-coordinated exposure studies, including the identification of selected chlorinated pesticides, dioxin-like compounds, industrial chemicals like polychlorinated biphenyls (PCB) and chlorinated paraffins, polybrominated POPs and PFAS, among others; and traces geographic, temporal and cross-substance trends and correlations, and human health risks. The book finishes by providing the reader with the summary of the main findings and outlook from these studies, in which the comparison of concentrations found for the wide range of POPs listed in the Stockholm Convention allowed the identification of possible needs for actions and follow-ups in different countries/regions. This book contributes to the understanding of exposure to hazardous chemicals and pollution as addressed by the UN Sustainable Development Goals on Good Health and Well-being (SDG 3) and will appeal to environmental and analytical chemists, researchers, professionals, and policymakers interested in learning more about contaminants in human milk. Given its breadth, this book will also appeal to a broader audience interested in maternal and child health.

Table of Contents

Part I Introduction -- Chapter 1 Human milk surveys on persistent organic pollutants from a historical perspective -- Chapter 2 Overview of WHO- and UNEP-coordinated human milk studies and their link to the Stockholm Convention on persistent organic pollutants -- Chapter 3 The Stockholm Convention, Global Monitoring Plan and its implementation in regional and global monitoring reports -- Part II Analytical methods and quality control -- Chapter 4 Analysis and quality control of WHO- and UNEP-coordinated human milk studies 2000–2019: polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans -- Chapter 5 Analysis and quality control of WHO- and UNEP-coordinated human milk studies 2000–2019: organochlorine pesticides and industrial chemicals -- Chapter 6 Analysis and quality control of WHO- and UNEP-coordinated human milk studies 2000–2019: polybrominated diphenylethers, hexabromocyclododecanes, chlorinated paraffins and polychlorinated naphthalenes -- Part III WHO/UNEP-coordinated exposure studies 2000–2019: results of chlorinated and brominated POPs and discussion -- Chapter 7 WHO- and UNEP-coordinated human milk studies 2000–2019: findings of polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans -- Chapter 8 WHO- and UNEP-coordinated human milk studies 2000–2019: findings of organochlorine pesticides and industrial chemicals -- Chapter 9 WHO- and UNEP-coordinated human milk studies 2000–2019: findings of polybrominated substances (PBDE, HBCDD, PBB 153, PBDD/PBDF) -- Chapter 10 WHO- and UNEP-coordinated human milk studies 2000–2019: findings of chlorinated paraffins -- Chapter 11 WHO- and UNEP-coordinated human milk studies 2000–2019: findings of polychlorinated naphthalenes -- Part IV Assessments -- Chapter 12 Time trends in human milk derived from WHO- and UNEP-coordinated exposure studies; Chapter 1: polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans -- Chapter 13 Time trends in human milk derived from WHO- and UNEP-coordinated exposure studies; Chapter 2: DDT, beta-HCH and HCB -- Chapter 14 Time trends in human milk derived from WHO- and UNEP-coordinated exposure studies; Chapter 3: perfluoroalkyl substances (PFAS) -- Chapter 15 Risk-benefit analysis for the breastfed infant based on the WHO- and UNEP human milk surveys for dioxin-like compounds -- Part V Summary, conclusions and outlook -- Chapter 16 Overall conclusions and key messages of the WHO/UNEP-coordinated human milk studies on persistent organic pollutants -- Chapter 17 Outlook (towards future studies on human milk).