Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach /

Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach / / edited by Konstantin Volcho, Olga Lavrik.

Although DNA repair enzymes play a crucial role in maintaining the integrity of the genome, the hyperactivity of certain enzymes of the DNA repair system can lead to the resistance of tumors to chemo- and radiotherapy, aimed at damaging the DNA of cancer cells. Therefore, the inhibition of DNA repai...

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Bibliographic Details
TeilnehmendeR:
Volcho, Olgax,
Volcho, Konstantin,
Place / Publishing House:Basel : : MDPI - Multidisciplinary Digital Publishing Institute,, 2023.
Year of Publication:2023
Language:English
Physical Description:1 online resource (316 pages)
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spelling Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach / edited by Konstantin Volcho, Olga Lavrik.
Basel : MDPI - Multidisciplinary Digital Publishing Institute, 2023.
1 online resource (316 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Description based on publisher supplied metadata and other sources.
Although DNA repair enzymes play a crucial role in maintaining the integrity of the genome, the hyperactivity of certain enzymes of the DNA repair system can lead to the resistance of tumors to chemo- and radiotherapy, aimed at damaging the DNA of cancer cells. Therefore, the inhibition of DNA repair enzymes could help to overcome this resistance. The reviews and research articles included in this collection describe the molecular mechanisms of action of some important enzymes of the DNA repair system, as well as some new inhibitors of such enzymes and the pharmacological properties of these inhibitors. This reprint clearly demonstrates the importance of the inhibition of DNA repair enzymes to fight various diseases, especially cancer.
Includes bibliographical references.
DNA replication Regulation.
3-0365-7880-3
Volcho, Olgax, editor.
Volcho, Konstantin, editor.
language English
format eBook
author2 Volcho, Olgax,
Volcho, Konstantin,
author_facet Volcho, Olgax,
Volcho, Konstantin,
author2_variant o v ov
k v kv
author2_role TeilnehmendeR
TeilnehmendeR
title Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach /
spellingShingle Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach /
title_full Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach / edited by Konstantin Volcho, Olga Lavrik.
title_fullStr Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach / edited by Konstantin Volcho, Olga Lavrik.
title_full_unstemmed Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach / edited by Konstantin Volcho, Olga Lavrik.
title_auth Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach /
title_new Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach /
title_sort inhibition of dna repair enzymes as a valuable pharmaceutical approach /
publisher MDPI - Multidisciplinary Digital Publishing Institute,
publishDate 2023
physical 1 online resource (316 pages)
isbn 3-0365-7880-3
callnumber-first Q - Science
callnumber-subject QP - Physiology
callnumber-label QP624
callnumber-sort QP 3624.5 R48 I545 42023
illustrated Not Illustrated
dewey-hundreds 500 - Science
dewey-tens 570 - Life sciences; biology
dewey-ones 572 - Biochemistry
dewey-full 572.8
dewey-sort 3572.8
dewey-raw 572.8
dewey-search 572.8
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