Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy : : Angiopathy Neuroimaging markers, cognitive features and rehabilitative issues / / Raffaella Valenti.

Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers i...

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Place / Publishing House:Florence : : Firenze University Press,, 2018.
Year of Publication:2018
Language:English
Physical Description:1 online resource (182 pages)
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Other title:Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy
Summary:Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers in the SVD, through a series of analyses from our five studies. Sporadic cerebral SVD is a complex 'micro-world' to be globally considered. All the relevant lesion types and SVD neuroimaging burden should be taken into account. The cumulative effects of microangiopathy burden in the brain of patients affected by SVD are crucial. Cognitive rehabilitation could represent a promising approach to prevent vascular dementia or to improve cognitive performances in patients with cerebral SVD. Longitudinal studies may provide more robust information about the progression and prognostic significance of our findings.
Hierarchical level:Monograph
Statement of Responsibility: Raffaella Valenti.