Molecular imaging in Parkinson's disease / / Cristina Polito.
The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychologi...
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| Place / Publishing House: | Firenze : : Firenze University Press,, 2011. |
| Year of Publication: | 2011 |
| Language: | English |
| Physical Description: | 1 online resource (68 pages) |
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| 100 | 1 | |a Polito, Cristina, |e author. | |
| 245 | 1 | 0 | |a Molecular imaging in Parkinson's disease / |c Cristina Polito. |
| 264 | 1 | |a Firenze : |b Firenze University Press, |c 2011. | |
| 300 | |a 1 online resource (68 pages) | ||
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| 588 | |a Description based on publisher supplied metadata and other sources. | ||
| 520 | |a The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET. First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus. | ||
| 650 | 0 | |a Parkinson's disease. | |
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