Histaminergic neurotransmission as a gateway for the effects of the fat sensing molecule Oleoylethanolamide : : Focus on cognition and stress-reactivity / / Alessia Costa.
The histaminergic system is a pleiotropic system that commands general states of metabolism and consciousness, including learning and memorizing both pleasurable and aversive events. Brain histamine mediates the central effects of a signal molecule produced in the intestine, namely oleoylethanolamid...
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| Superior document: | Premio Tesi di Dottorato |
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| VerfasserIn: | |
| Place / Publishing House: | Florence : : Firenze University Press,, 2019. |
| Year of Publication: | 2019 |
| Language: | English |
| Series: | Premio Tesi di Dottorato.
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| Physical Description: | 1 online resource (124 pages). |
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| Other title: | Histaminergic neurotransmission as a gateway for the effects of the fat sensing molecule Oleoylethanolamide |
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| Summary: | The histaminergic system is a pleiotropic system that commands general states of metabolism and consciousness, including learning and memorizing both pleasurable and aversive events. Brain histamine mediates the central effects of a signal molecule produced in the intestine, namely oleoylethanolamide (OEA). OEA is released by the enterocytes in response to high fat intake and reduces eating, by indirectly activating a subpopulation of histaminergic neurons. In her thesis, she explored other potential interactions between these two systems in the pursuit of unexplored neuronal mechanisms that may shed light on the mode of action of psychoactive agents and possibly lead to the development of new drugs. |
| Hierarchical level: | Monograph |
| Statement of Responsibility: | Alessia Costa. |