Biology of Trypanosoma cruzi / / edited by Wanderley de Souza.
Trypanosoma cruzi, an important zoonotic protozoan that causes Chagas disease, affects at least 8 million people in Latin America. Chagas disease is an important life-long infection in humans that can be divided into distinct clinical stages: the acute phase, where patient symptoms can vary from asy...
Saved in:
TeilnehmendeR: | |
---|---|
Place / Publishing House: | London : : IntechOpen,, 2019. |
Year of Publication: | 2019 |
Language: | English |
Physical Description: | 1 online resource (234 pages) |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993603391204498 |
---|---|
ctrlnum |
(CKB)5410000000364667 (NjHacI)995410000000364667 (EXLCZ)995410000000364667 |
collection |
bib_alma |
record_format |
marc |
spelling |
Biology of Trypanosoma cruzi / edited by Wanderley de Souza. London : IntechOpen, 2019. 1 online resource (234 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on online resource; title from PDF title page (IntechOpen, viewed June 25, 2023). Trypanosoma cruzi, an important zoonotic protozoan that causes Chagas disease, affects at least 8 million people in Latin America. Chagas disease is an important life-long infection in humans that can be divided into distinct clinical stages: the acute phase, where patient symptoms can vary from asymptomatic to severe; the indeterminate form, which is usually asymptomatic; and the chronic phase, where cardiomyopathy and/or digestive megasyndromes appear. In addition to its medical importance, T. cruzi is an interesting biological model for studying processes such as: (1) cell differentiation, where a non-infective stage transforms into an infective one; (2) cell invasion, where the infective stages are able to penetrate into a mammalian host cell, where they multiply several times and thus amplify the infection; and (3) evasion from the immune system, using several mechanisms. This book, with 13 chapters, has been organized in four major sections: 1. "Basic Biology," 2. "Biochemistry and Molecular Biology," 3. "Parasite"Host Cell Interaction," and 4 "Chemotherapy." The chapters include basic biological information on the protozoan lifecycle, including new information on parasite genomics and proteomics. In addition, they analyze the interaction with host cells as well the immune response and evasion, ending with information on experimental chemotherapy against Chagas disease. Trypanosoma cruzi. 1-83968-205-1 Souza, Wanderley de, editor. |
language |
English |
format |
eBook |
author2 |
Souza, Wanderley de, |
author_facet |
Souza, Wanderley de, |
author2_variant |
w d s wd wds |
author2_role |
TeilnehmendeR |
title |
Biology of Trypanosoma cruzi / |
spellingShingle |
Biology of Trypanosoma cruzi / |
title_full |
Biology of Trypanosoma cruzi / edited by Wanderley de Souza. |
title_fullStr |
Biology of Trypanosoma cruzi / edited by Wanderley de Souza. |
title_full_unstemmed |
Biology of Trypanosoma cruzi / edited by Wanderley de Souza. |
title_auth |
Biology of Trypanosoma cruzi / |
title_new |
Biology of Trypanosoma cruzi / |
title_sort |
biology of trypanosoma cruzi / |
publisher |
IntechOpen, |
publishDate |
2019 |
physical |
1 online resource (234 pages) |
isbn |
1-83968-205-1 |
callnumber-first |
Q - Science |
callnumber-subject |
QL - Zoology |
callnumber-label |
QL368 |
callnumber-sort |
QL 3368 K5 B565 42019 |
illustrated |
Not Illustrated |
dewey-hundreds |
500 - Science |
dewey-tens |
590 - Animals (Zoology) |
dewey-ones |
593 - Marine & seashore invertebrates |
dewey-full |
593.18 |
dewey-sort |
3593.18 |
dewey-raw |
593.18 |
dewey-search |
593.18 |
work_keys_str_mv |
AT souzawanderleyde biologyoftrypanosomacruzi |
status_str |
n |
ids_txt_mv |
(CKB)5410000000364667 (NjHacI)995410000000364667 (EXLCZ)995410000000364667 |
carrierType_str_mv |
cr |
is_hierarchy_title |
Biology of Trypanosoma cruzi / |
author2_original_writing_str_mv |
noLinkedField |
_version_ |
1796653218109849600 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02294nam a2200277 i 4500</leader><controlfield tag="001">993603391204498</controlfield><controlfield tag="005">20230625195734.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr |||||||||||</controlfield><controlfield tag="008">230625s2019 enk o 000 0 eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)5410000000364667</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(NjHacI)995410000000364667</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)995410000000364667</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">NjHacI</subfield><subfield code="b">eng</subfield><subfield code="e">rda</subfield><subfield code="c">NjHacl</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">QL368.K5</subfield><subfield code="b">.B565 2019</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">593.18</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="0" ind2="0"><subfield code="a">Biology of Trypanosoma cruzi /</subfield><subfield code="c">edited by Wanderley de Souza.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">London :</subfield><subfield code="b">IntechOpen,</subfield><subfield code="c">2019.</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (234 pages)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="588" ind1=" " ind2=" "><subfield code="a">Description based on online resource; title from PDF title page (IntechOpen, viewed June 25, 2023).</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Trypanosoma cruzi, an important zoonotic protozoan that causes Chagas disease, affects at least 8 million people in Latin America. Chagas disease is an important life-long infection in humans that can be divided into distinct clinical stages: the acute phase, where patient symptoms can vary from asymptomatic to severe; the indeterminate form, which is usually asymptomatic; and the chronic phase, where cardiomyopathy and/or digestive megasyndromes appear. In addition to its medical importance, T. cruzi is an interesting biological model for studying processes such as: (1) cell differentiation, where a non-infective stage transforms into an infective one; (2) cell invasion, where the infective stages are able to penetrate into a mammalian host cell, where they multiply several times and thus amplify the infection; and (3) evasion from the immune system, using several mechanisms. This book, with 13 chapters, has been organized in four major sections: 1. "Basic Biology," 2. "Biochemistry and Molecular Biology," 3. "Parasite"Host Cell Interaction," and 4 "Chemotherapy." The chapters include basic biological information on the protozoan lifecycle, including new information on parasite genomics and proteomics. In addition, they analyze the interaction with host cells as well the immune response and evasion, ending with information on experimental chemotherapy against Chagas disease.</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Trypanosoma cruzi.</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">1-83968-205-1</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Souza, Wanderley de,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-07-06 03:31:33 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2022-01-15 21:49:20 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338241030004498&Force_direct=true</subfield><subfield code="Z">5338241030004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338241030004498</subfield></datafield></record></collection> |