Updated View on an Emerging Target : : Selected Papers from the 8th International Conference on Protein Kinase CK2 / / edited by Joachim Jose [and three others].
The 8th International Conference on Protein Kinase CK2 (www.uks.eu/ck2), organized by Matthias Montenarh and Claudia Götz, will be held at the Faculty of Medicine of Saarland University, in Homburg, Germany, from 6-9 September, 2016. Protein kinase CK2 is a serine/threonine kinase, which is highly...
Saved in:
TeilnehmendeR: | |
---|---|
Place / Publishing House: | Basel : : MDPI - Multidisciplinary Digital Publishing Institute,, 2017. ©2017 |
Year of Publication: | 2017 |
Language: | English |
Physical Description: | 1 online resource (xiii, 320 pages) :; illustrations |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993603389904498 |
---|---|
ctrlnum |
(CKB)5400000000045816 (NjHacI)995400000000045816 (EXLCZ)995400000000045816 |
collection |
bib_alma |
record_format |
marc |
spelling |
Updated View on an Emerging Target : Selected Papers from the 8th International Conference on Protein Kinase CK2 / edited by Joachim Jose [and three others]. Updated View on an Emerging Target Basel : MDPI - Multidisciplinary Digital Publishing Institute, 2017. ©2017 1 online resource (xiii, 320 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on publisher supplied metadata and other sources. The 8th International Conference on Protein Kinase CK2 (www.uks.eu/ck2), organized by Matthias Montenarh and Claudia Götz, will be held at the Faculty of Medicine of Saarland University, in Homburg, Germany, from 6-9 September, 2016. Protein kinase CK2 is a serine/threonine kinase, which is highly conserved in evolution. Knock-out experiments have shown that this enzyme is absolutely necessary for cell viability. The enzyme is highly expressed in rapidly proliferating cells, which goes along with an elevated enzyme activity. Protein kinase CK2 is involved in a broad range of signaling pathways, regulating proliferation, differentiation, apoptosis, or senescence. Recent advances towards the characterization of the three-dimensional structure of protein kinase CK2 and its subunits will undoubtedly yield important new insights into its regulation, and the functions of CK2. Moreover, with two inhibitors of the enzyme presently in clinical phase II trials, human protein kinase CK2 has appeared as an emerging target for cancer diseases. Includes bibliographical references. Protein kinase CK2. 3-03842-412-9 Jose, Joachim, editor. |
language |
English |
format |
eBook |
author2 |
Jose, Joachim, |
author_facet |
Jose, Joachim, |
author2_variant |
j j jj |
author2_role |
TeilnehmendeR |
title |
Updated View on an Emerging Target : Selected Papers from the 8th International Conference on Protein Kinase CK2 / |
spellingShingle |
Updated View on an Emerging Target : Selected Papers from the 8th International Conference on Protein Kinase CK2 / |
title_sub |
Selected Papers from the 8th International Conference on Protein Kinase CK2 / |
title_full |
Updated View on an Emerging Target : Selected Papers from the 8th International Conference on Protein Kinase CK2 / edited by Joachim Jose [and three others]. |
title_fullStr |
Updated View on an Emerging Target : Selected Papers from the 8th International Conference on Protein Kinase CK2 / edited by Joachim Jose [and three others]. |
title_full_unstemmed |
Updated View on an Emerging Target : Selected Papers from the 8th International Conference on Protein Kinase CK2 / edited by Joachim Jose [and three others]. |
title_auth |
Updated View on an Emerging Target : Selected Papers from the 8th International Conference on Protein Kinase CK2 / |
title_alt |
Updated View on an Emerging Target |
title_new |
Updated View on an Emerging Target : |
title_sort |
updated view on an emerging target : selected papers from the 8th international conference on protein kinase ck2 / |
publisher |
MDPI - Multidisciplinary Digital Publishing Institute, |
publishDate |
2017 |
physical |
1 online resource (xiii, 320 pages) : illustrations |
isbn |
3-03842-412-9 |
callnumber-first |
Q - Science |
callnumber-subject |
QP - Physiology |
callnumber-label |
QP606 |
callnumber-sort |
QP 3606 P76 U633 42017 |
illustrated |
Illustrated |
dewey-hundreds |
500 - Science |
dewey-tens |
570 - Life sciences; biology |
dewey-ones |
572 - Biochemistry |
dewey-full |
572.76 |
dewey-sort |
3572.76 |
dewey-raw |
572.76 |
dewey-search |
572.76 |
work_keys_str_mv |
AT josejoachim updatedviewonanemergingtargetselectedpapersfromthe8thinternationalconferenceonproteinkinaseck2 AT josejoachim updatedviewonanemergingtarget |
status_str |
n |
ids_txt_mv |
(CKB)5400000000045816 (NjHacI)995400000000045816 (EXLCZ)995400000000045816 |
carrierType_str_mv |
cr |
is_hierarchy_title |
Updated View on an Emerging Target : Selected Papers from the 8th International Conference on Protein Kinase CK2 / |
author2_original_writing_str_mv |
noLinkedField |
_version_ |
1796653225786474497 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02147nam a2200301 i 4500</leader><controlfield tag="001">993603389904498</controlfield><controlfield tag="005">20230625023442.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr |||||||||||</controlfield><controlfield tag="008">230625s2017 sz a ob 000 0 eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)5400000000045816</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(NjHacI)995400000000045816</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)995400000000045816</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">NjHacI</subfield><subfield code="b">eng</subfield><subfield code="e">rda</subfield><subfield code="c">NjHacl</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">QP606.P76</subfield><subfield code="b">.U633 2017</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">572.76</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="0" ind2="0"><subfield code="a">Updated View on an Emerging Target :</subfield><subfield code="b">Selected Papers from the 8th International Conference on Protein Kinase CK2 /</subfield><subfield code="c">edited by Joachim Jose [and three others].</subfield></datafield><datafield tag="246" ind1=" " ind2=" "><subfield code="a">Updated View on an Emerging Target</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Basel :</subfield><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute,</subfield><subfield code="c">2017.</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">©2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (xiii, 320 pages) :</subfield><subfield code="b">illustrations</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="588" ind1=" " ind2=" "><subfield code="a">Description based on publisher supplied metadata and other sources.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The 8th International Conference on Protein Kinase CK2 (www.uks.eu/ck2), organized by Matthias Montenarh and Claudia Götz, will be held at the Faculty of Medicine of Saarland University, in Homburg, Germany, from 6-9 September, 2016. Protein kinase CK2 is a serine/threonine kinase, which is highly conserved in evolution. Knock-out experiments have shown that this enzyme is absolutely necessary for cell viability. The enzyme is highly expressed in rapidly proliferating cells, which goes along with an elevated enzyme activity. Protein kinase CK2 is involved in a broad range of signaling pathways, regulating proliferation, differentiation, apoptosis, or senescence. Recent advances towards the characterization of the three-dimensional structure of protein kinase CK2 and its subunits will undoubtedly yield important new insights into its regulation, and the functions of CK2. Moreover, with two inhibitors of the enzyme presently in clinical phase II trials, human protein kinase CK2 has appeared as an emerging target for cancer diseases.</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references.</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Protein kinase CK2.</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-03842-412-9</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Jose, Joachim,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-07-06 03:30:54 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2022-04-04 09:22:53 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338080950004498&Force_direct=true</subfield><subfield code="Z">5338080950004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338080950004498</subfield></datafield></record></collection> |