The cost manual of laboratory animal care and use : : refinement, reduction, and research / / edited by Bryan Howard, Timo Nevalainen, Gemma Perretta.

• TeilnehmendeR: Howard, Bryan,; Nevalainen, Timo,; Perretta, Gemma,
• Place / Publishing House: Boca Raton, FL : : Taylor and Francis, an imprint of CRC Press,, 2010.
• Year of Publication: 2010
• Language: English
• Physical Description: 1 online resource (439 pages) :; illustrations

COST (European Cooperation in the field of Scientific and Technical Research) is an intergovernmental initiative in science and research intended to promote the coordination of nationally funded research in Europe.

Table of Contents

Chapter 1 Introduction -- chapter 2 Design and Oversight of Laboratory Animal Facilities -- chapter 3 Housing and Care of Laboratory Animals -- chapter 4 Animal Needs and Environmental Refinement -- chapter 5 Ethical Evaluation of ScientificProcedures: Recommendations for Ethics Committees -- chapter 6 Reduction by Careful Design and Statistical Analysis -- chapter 7 Animal Models: Selecting and Preparing Animals for a Study -- chapter 8 Creation of Genetically Modified Animals -- chapter 9 Management of Genetically Modified Rodents -- chapter 10 Impact of Handling, Radiotelemetry, and Food Restriction -- chapter 11 Basic Procedures: Dosing, Sampling and Immunisation -- chapter 12 Imaging Techniques -- chapter 13 Anaesthesia and Analgesia -- chapter 14 Use of Humane Endpointsto Minimise Suffering -- chapter 15 Euthanasia -- chapter 16 Education, Training, and Competence -- chapter 17 Animal Experimentation and Open Communication.