Evolution of Epigenome as the Blueprint for Carcinogenesis /

Evolution of Epigenome as the Blueprint for Carcinogenesis / / written by Zeenat Farooq [and four others].

Epigenetics "above or over genetics" is the term used for processes that result in modifications which are stably inherited through cell generations, without changing the underlying DNA sequence of the cell. These include DNA methylation, Post-translational histone modification and non-cod...

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Bibliographic Details
VerfasserIn:
Farooq, Zeenat,
Place / Publishing House:London : : IntechOpen,, 2021.
Year of Publication:2021
Language:English
Physical Description:1 online resource (176 pages)
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Table of Contents:
  • 1. Introduction
  • 2. Epigenetics and chromatin biology: unifying themes and differences
  • 3. DNA methylation
  • 4. Epigenetic modifications in context of chromatin
  • 4.1 Histone modifications
  • 4.1.1 Histone acetylation and deacetylation
  • 4.1.2 HATs, HDACs and cancer
  • 4.1.3 Histone methylation
  • 4.1.4 HMTs and cancer
  • 4.1.5 Histone phosphorylation
  • 4.1.6 Histone phosphorylation and cancer
  • 4.1.7 Histone ubiquitination
  • 4.1.8 Histone ubiquitination and cancer
  • 5. Conclusion
  • References.

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