Organoid bioengineering : : advances, applications and challenges / / edited by Manash K. Paul.

• Superior document: IntechOpen book series. Biomedical engineering ; Volume 13
• TeilnehmendeR: Paul, Manash K.,
• Place / Publishing House: London : : IntechOpen,, [2022]; ©2022
• Year of Publication: 2022
• Language: English
• Series: IntechOpen book series. Biomedical engineering ; Volume 13.
• Physical Description: 1 online resource (136 pages).

Organoids are three-dimensional miniature tissue mimics established from embryonic stem cells, human pluripotent stem cells, adult stem cells, and cancer cells. These fascinating 3D organoids serve as a valuable tool for fundamental research, disease modelling, drug screening and discovery, regenerative medicine, and deciphering the mechanism of disease pathogenesis. This book emphasizes the emerging data and critical resources covering the fundamentals of organoids and their use in modeling and application in various diseases, especially cancer. The chapters deal with organoid bioengineering in cerebral organoids, retinal organoids, tumoroids, and organoid commercialization. This book is intended for a broad readership and is an indispensable resource for basic biologists, translational scientists, and clinicians.

Table of Contents

1. Introductory Chapter: Organoid Technology and Potential Applications. 2. Applications of Neural Organoids in Neurodevelopment and Regenerative Medicine. 3. The Brain Organoid Technology: Diversity of Protocols and Challenges. 4. Retinal Organoids over the Decade. 5. Evolution of Organoids in Oncology. 6. Organoids and Commercialization.