Ion transporters : : from basic properties to medical treatment / / edited by Zuzana Ševčíková Tomášková.

• TeilnehmendeR: Tomášková, Zuzana Ševčíková,
• Place / Publishing House: London : : IntechOpen,, [2022]; ©2022
• Year of Publication: 2022
• Language: English
• Physical Description: 1 online resource (194 pages)

Ion transporters are membrane proteins that allow the passage of ions or charged small molecules through the lipid membrane. They are present in every cell of every organism. The group of ion transporters comprises different types of ion pumps, ion exchangers, and ion channels. This book focuses mostly on ion channels, which represent the biggest subset of ion transporters. Ion transporters, especially ion channels, are of imminent interest in the field of life sciences with possible therapeutic outcomes. Each piece of knowledge that can help us understand their role and function is worth noticing. This book provides a comprehensive overview of ion channels, including their diversity and functions in physiology and pathophysiology.

Table of Contents

1. Ion Channels and Neurodegenerative Disease Aging Related. 2. Mitochondrial Channels and Their Role in Cardioprotection. 3. Hot on the Trail of Skin Inflammation: Focus on TRPV1/TRPV3 Channels in Psoriasis. 4. TRPV Family Ion Channels in the Mammary Epithelium: Role in Normal Tissue Homeostasis and along Breast Cancer Progression. 5. SK Channels and Heart Disease. 6. Vacuolar ATPase (V-ATPase) Proton Pump and Its Significance in Human Health. 7. Structural Determinants for Ligand Accommodation in Voltage Sensors.