Recent advances in noncoding RNAs / / edited by Lutfi Tutar.

• TeilnehmendeR: Tutar, Lutfi,
• Place / Publishing House: London : : IntechOpen,, 2022.
• Year of Publication: 2022
• Language: English
• Physical Description: 1 online resource (236 pages)

The discovery of noncoding RNAs (ncRNAs) is changed our understanding of genome, transcriptome, and interactions with proteome in a cell. Since the discovery of the first microRNA (miRNA) called lin-4 on Caenorhabditis elegans in 1993, our understanding of gene expression has deepened. Further miRNA discoveries have led to the investigation of new ncRNA families and their function, biogenesis, and interactions with other types of molecules. Recent developments in bioinformatics, public databases, sequencing technologies, and biochemical techniques have increased our understanding of the biogenesis, function, and interactions of ncRNAs. This book provides an overview of current ncRNA research dealing with human diseases and cancer and plant miRNAs.

Table of Contents

1. Introductory Chapter: Noncoding RNAs-A Brief Introduction -- 2. Long Non-Coding RNAs: Biogenesis, Mechanism of Action and Role in Different Biological and Pathological Processes -- 3. Advantages of Noncoding RNAs in Molecular Diagnosis -- 4. Role of Non-Coding RNAs in Lung Cancer -- 5. MicroRNAs and Pancreatic ß Cell Functional Modulation -- 6. Predicting SNPs in Mature MicroRNAs Dysregulated in Breast Cancer -- 7. Long Non-Coding RNA in Neural Stem Cells Self-Renewal, Neurogenesis, Gliogenesis and Synaptogenesis -- 8. Interactions of lncRNAs and miRNAs in Digestive System Tumors -- 9. MicroRNAs and Male Infertility -- 10. The Role of Noncoding RNAs in the Response of Oil Palm Plants to Abiotic Stresses.